Design of the Surface of Particles in the Emulsion Polymerization of Methyl Methacrylate in the Presence of Carboxylated Dextran Derivatives
Polymer Science Series A
, E-ISSN: 1555-6107
Institute of High Molecular Weight Compounds RAS
St. Petersburg Department of G.K. Boreskov Institute of Catalysis SB RAS
It was shown that carboxylated dextran derivatives used as polymer stabilizers can significantly accelerate the emulsion polymerization of methyl methacrylate initiated by 4,4'-azo-bis(4-cyanisovaleric acid). It was proposed that the process proceeds via the microemulsion mechanism. By varying the structure of a dextran derivative and its concentration in the reaction mixture, one can accomplish the targeted design of submicron monodisperse particles and can influence the structure of their surface. Using the microelectrophoresis method, it was established that the surface carboxyl groups located on polysaccharide chains exhibit an enhanced mobility. The adsorption and covalent binding of a protein by the surface of the obtained particles were studied, and their efficiency as adjuvant immunoreagent carriers was demonstrated.