Investigation of Polymer Hydrogels with Memory Effect for Cefazolin Immobilization by Small-Angle Neutron Scattering Full article
Journal |
Journal of Surface Investigation: X-Ray, Synchrotron and Neutron Techniques
ISSN: 1027-4510 , E-ISSN: 1819-7094 |
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Output data | Year: 2012, Volume: 6, Number: 5, Pages: 825-832 Pages count : 8 DOI: 10.1134/S1027451012100102 | ||||||
Tags | Carboxylic acids; Neutron scattering; Sorption | ||||||
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Abstract:
The method of small-angle neutron scattering has been used for the investigation of hydrogels synthesized on the basis of a cross-linked copolymer of 2-hydroxyethyl methacrylate and functional monomers (acrylic acid or dimethylaminoethyl methacrylate) which possess the memory effect with respect to the target pharmaceutical substance — cefazolin. The difference in the structure of anionic, cationic and amphiphilic hydrogels has been shown as well as the relation between the structure and the ability of a hydrogel for water sorption in the presence and in the absence of cefazolin. Certain structural features of the hydrogels confirmed the conditions for the appearance of the memory effect for the sorption and liberation of cefazolin.
Cite:
Kul'velis Y.V.
, Lebedev V.T.
, Trunov V.A.
, Ivanchev S.S.
, Primachenko O.N.
, Khaikin S.Y.
Investigation of Polymer Hydrogels with Memory Effect for Cefazolin Immobilization by Small-Angle Neutron Scattering
Journal of Surface Investigation: X-Ray, Synchrotron and Neutron Techniques. 2012. V.6. N5. P.825-832. DOI: 10.1134/S1027451012100102 WOS Scopus РИНЦ
Investigation of Polymer Hydrogels with Memory Effect for Cefazolin Immobilization by Small-Angle Neutron Scattering
Journal of Surface Investigation: X-Ray, Synchrotron and Neutron Techniques. 2012. V.6. N5. P.825-832. DOI: 10.1134/S1027451012100102 WOS Scopus РИНЦ
Original:
Кульвелис Ю.
, Лебедев В.Т.
, Трунов В.А.
, Иванчев С.С.
, Примаченко О.Н.
, Хайкин С.Я.
Исследование полимерных гидрогелей, обладающих эффектом памяти для иммобилизации цефазолина, методом малоуглового рассеяния нейтронов.
Поверхность. Рентгеновские, синхротронные и нейтронные исследования. 2012. №10. С.45-52. РИНЦ
Исследование полимерных гидрогелей, обладающих эффектом памяти для иммобилизации цефазолина, методом малоуглового рассеяния нейтронов.
Поверхность. Рентгеновские, синхротронные и нейтронные исследования. 2012. №10. С.45-52. РИНЦ
Dates:
Submitted: | Jan 12, 2012 |
Published print: | Sep 1, 2012 |
Published online: | Oct 10, 2012 |
Identifiers:
Web of science | WOS:000309721400021 |
Scopus | 2-s2.0-84867410065 |
Elibrary | 20495425 |
Chemical Abstracts | 2012:1479765 |
Chemical Abstracts (print) | 158:21643 |
OpenAlex | W2033210335 |