Morphological Assessment of Influence of Carbon Nanofibers on Digestive Organs of Wistar Rats upon Oral Administration Full article
Journal |
Biology and Medicine
ISSN: 0974-8369 |
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Output data | Year: 2015, Volume: 7, Number: 2, Article number : BM-075-15: 1-5, Pages count : 5 | ||||||||
Tags | Carbon nanofibers, Toxicity, Wistar rats | ||||||||
Authors |
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Affiliations |
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Funding (3)
1 | Far Eastern Federal University | 13-06-0318 |
2 | Far Eastern Federal University | 14-08-02-24 |
3 | The Ministry of Education and Science of the Russian Federation | 14.594.21.0006 (114120470079) |
Abstract:
The results of research on three types of carbon nanofibers influence on an organism of Wistar rats at oral intro¬duction with food in a dose of 500 mg per kilogram of a body weight within 14 days are presented. According to the results of electronic microscopy, carbon nanofibers had the following linear sizes: an average diameter is 85 nm and a length is about 5-50 μm. The influence of nanofibers on a histologic structure of stomach, intestines, and liver of rats is shown. The response to mechanical irritation is noted in signs as follows: raised mucus production, mucosal thickening, lymphoid follicles enlargement, vacuolation and necrosis in some cases.
Cite:
Golokhvast K.S.
, Sayapina N.V.
, Batalova T.A.
, Sergievich A.A.
, Mishakov I.V.
, Vedyagin A.A.
, Novikov M.A.
, Agoshkov A.I.
, Petukhov V.I.
, Drozd V.A.
, Ugay S.M.
, Chaika V.V.
Morphological Assessment of Influence of Carbon Nanofibers on Digestive Organs of Wistar Rats upon Oral Administration
Biology and Medicine. 2015. V.7. N2. BM-075-15: 1-5 :1-5. Scopus РИНЦ
Morphological Assessment of Influence of Carbon Nanofibers on Digestive Organs of Wistar Rats upon Oral Administration
Biology and Medicine. 2015. V.7. N2. BM-075-15: 1-5 :1-5. Scopus РИНЦ
Dates:
Submitted: | Jan 23, 2015 |
Accepted: | Feb 23, 2015 |
Published print: | Apr 13, 2015 |
Identifiers:
Scopus | 2-s2.0-84928729407 |
Elibrary | 24026568 |