The Effects of Tableting with Potassium Bromide on the Infrared Absorption Spectra of Indomethacin Full article
| Journal |
Pharmaceutical Chemistry Journal
ISSN: 0091-150X , E-ISSN: 1573-9031 |
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| Output data | Year: 2009, Volume: 43, Number: 1, Pages: 68-70 Pages count : 3 DOI: 10.1007/s11094-009-0225-z | ||||||
| Tags | Indomethacin, IR spectra, Potassium bromide, Tableting | ||||||
| Authors |
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| Affiliations |
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Funding (4)
| 1 | Russian Foundation for Basic Research | 07-03-00160 |
| 2 | The Ministry of Education and Science of the Russian Federation | 2.1.1.4935 |
| 3 | Президиум РАН | |
| 4 | Civilian Research and Development Foundation | NO-008-X1 |
Abstract:
The effects of tableting with KBr on the IR absorption spectra of molecular crystals were studied at room temperature. Study substances were mechanically activated mixtures of crystalline indomethacin and the excipient polyethylene glycol at ratios of 1:1 and 1:3. There was a marked widening of absorption bands in the range 2000–500 cm−1 in the IR spectra of mechanically activated mixtures in tablets with KBr. These experimental results are assessed within the framework of possible interactions between study samples and the KBr matrix during tableting and storage as powered mixtures.
Cite:
Fedotov A.P.
, Shakhtshneider T.P.
, Chesalov Y.A.
, Surov E.V.
The Effects of Tableting with Potassium Bromide on the Infrared Absorption Spectra of Indomethacin
Pharmaceutical Chemistry Journal. 2009. V.43. N1. P.68-70. DOI: 10.1007/s11094-009-0225-z WOS Scopus РИНЦ ANCAN OpenAlex
The Effects of Tableting with Potassium Bromide on the Infrared Absorption Spectra of Indomethacin
Pharmaceutical Chemistry Journal. 2009. V.43. N1. P.68-70. DOI: 10.1007/s11094-009-0225-z WOS Scopus РИНЦ ANCAN OpenAlex
Original:
Федотов А.П.
, Шахтшнейдер Т.П.
, Чесалов Ю.А.
, Суров Е.В.
О влиянии таблетирования с бромидом калия на инфракрасные спектры поглощения индометацина
Химико-фармацевтический журнал. 2009. Т.43. №1. С.50-52. RSCI РИНЦ
О влиянии таблетирования с бромидом калия на инфракрасные спектры поглощения индометацина
Химико-фармацевтический журнал. 2009. Т.43. №1. С.50-52. RSCI РИНЦ
Dates:
| Submitted: | Apr 27, 2007 |
| Published print: | Jan 1, 2009 |
| Published online: | May 6, 2009 |
Identifiers:
| Web of science: | WOS:000266142900019 |
| Scopus: | 2-s2.0-67349200249 |
| Elibrary: | 13606293 |
| Chemical Abstracts: | 2009:552114 |
| Chemical Abstracts (print): | 151:131829 |
| OpenAlex: | W1978909764 |