Small-Angle Neutron Scattering from Polymer Hydrogels with Memory Effect for Medicine Immobilization Научная публикация
Журнал |
Crystallography Reports
ISSN: 1063-7745 , E-ISSN: 1562-689X |
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Вых. Данные | Год: 2011, Том: 56, Номер: 7, Страницы: 1114-1117 Страниц : 9 DOI: 10.1134/S1063774511070170 | ||||||
Ключевые слова | DRUG-DELIVERY; CONTACT-LENSES; RELEASE | ||||||
Авторы |
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Организации |
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Реферат:
Hydrogels synthesized based on cross-linked copolymers of 2-hydroxyethyl methacrylate and functional monomers (acrylic acid or dimethylaminoethyl methacrylate), having a memory effect with respect to target medicine (cefazolin), have been investigated by small-angle neutron scattering. The hydrogels are found to have a two-level structural organization: large (up to 100 nm) aggregates filled with network cells (4–7 nm in size). The structural differences in the anionic, cationic, and amphiphilic hydrogels and the relationship between their structure and the ability of hydrogels to absorb moisture are shown. A relationship between the memory effect during cefazolin immobilization and the internal structure of hydrogels, depending on their composition and type of functional groups, is established.
Библиографическая ссылка:
Kulvelis Y.V.
, Lebedev V.T.
, Trunov V.A.
, Pavlyuchenko V.N.
, Ivanchev S.S.
, Primachenko O.N.
, Khaikin S.Y.
Small-Angle Neutron Scattering from Polymer Hydrogels with Memory Effect for Medicine Immobilization
Crystallography Reports. 2011. V.56. N7. P.1114-1117. DOI: 10.1134/S1063774511070170 WOS Scopus РИНЦ
Small-Angle Neutron Scattering from Polymer Hydrogels with Memory Effect for Medicine Immobilization
Crystallography Reports. 2011. V.56. N7. P.1114-1117. DOI: 10.1134/S1063774511070170 WOS Scopus РИНЦ
Даты:
Поступила в редакцию: | 16 дек. 2010 г. |
Опубликована online: | 19 нояб. 2011 г. |
Опубликована в печати: | 1 дек. 2011 г. |
Идентификаторы БД:
Web of science | WOS:000297372800007 |
Scopus | 2-s2.0-84856726288 |
РИНЦ | 18034949 |
Chemical Abstracts | 2011:1488233 |
Chemical Abstracts (print) | 157:176825 |
OpenAlex | W2071079403 |