Cellulose Biorefinery Based on Combined Catalytic and Biotechnological Approach for Production of 5-HMF and Ethanol
Science article
| Общее |
Language:
Английский,
Genre:
Full article,
Status:
Published,
Source type:
Original
|
| Journal |
ChemSusChem
ISSN: 1864-5631
, E-ISSN: 1864-564X
|
| Output data |
Year: 2017,
Volume: 10,
Number: 3,
Pages: 562-574
Pages count
: 13
DOI:
10.1002/cssc.201601244
|
| Tags |
5-HMF, biomass conversion, biosynthesis, ethanol, heterogeneous catalysis |
| Authors |
Sorokina Ksenia N.
1,2
,
Taran Oxana P.
1,3
,
Medvedeva Tatiana B.
1
,
Samoylova Yuliya V.
1
,
Piligaev Alexandr V.
1
,
Parmon Valentin N.
1,2
|
| Affiliations |
| 1 |
Boreskov Institute of Catalysis (BIC) 630090, Novosibirsk, Lavrentieva ave. 5 (Russian Federation)
|
| 2 |
Novosibirsk State University (NSU) 630090, Novosibirsk, Pirogova str. 2 (Russian Federation)
|
| 3 |
Novosibirsk State Technical University (NSTU) 630037, Novosibirsk, Prosp. Karla Marksa, 20 (Russian Federation)
|
|
Funding (1)
|
1
|
The Ministry of Education and Science of the Russian Federation
|
14.613.21.0017 (RFMEFI61314X0017)
|
In this study, a combination of catalytic and biotechnological processes was proposed for the first time for application in a cellulose biorefinery for the production of 5-HMF and bioethanol. Hydrolytic dehydration of the mechanically activated microcrystalline cellulose over a carbon-based mesoporous Sibunt-4 catalyst resulted in moderate yields of glucose and 5-HMF (21.1-25.1% and 6.6-9.4%). 5-HMF was extracted from the resulting mixture with isobutanol and subjected to ethanol fermentation. A number of yeast strains were isolated that also revealed high thermotolerance (up to 50°C) and resistance to inhibitors found in the hydrolysates. The strains Kluyveromyces marxianus C1 and Ogataea polymorpha CBS4732 are capable of producing ethanol on processed catalytic hydrolysates of cellulose at 42°C, with yields of 72.0±5.7% and 75.2±4.3% from the maximum theoretical yield of ethanol, respectively.