NMR Studies of Transformations of Aminoacid Complexes of Pt(II) and Pd(ll) in Solution. 2. Bisalaninates
Journal of Structural Chemistry
, E-ISSN: 1573-8779
Novosibirsk State University
Synthetic procedures are suggested for diastereomers of Pt(H) and Pd(H) bischelates with alanine: cis and trans-Pt(l-Ala) 2 , trans-Pt(I-Ala)(d-Ala), trans-Pd(I-Ala)2 , and trans-Pd(l-Ala)(d-Ala). Methods of their isolation in individual solid state are proposed. 1H, 13C, and 195Pt NMR spectral investigations are reported for the individual diastereomers and for M(Ala) 2 racemates in DMSO solution. The trans-isomers of Pd(H) bisalaninates in DMSO solution are transformed into an equilibrium mixture of cis- and trans-isomers. For Pt(ll) complexes, the cis ~ o'ans equilibrium was also found but the equilibration rate is much lower than that for Pd(H) bischelates for both cis- and trans-isomer. An equilibrium
2M(I-Ala)(d-Ala) -><- M(I-Ala)2+M(d-Ala) 2 is also shown to exist.