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Synthesis of Secondary Amines by Reductive Amination of Aldehydes with Nitroarenes over Supported Copper Catalysts in a Flow Reactor Full article

Общее Language: Английский, Genre: Full article,
Status: Published, Source type: Original
Journal Catalysis Communications
ISSN: 1566-7367 , E-ISSN: 1873-3905
Output data Year: 2017, Volume: 102, Pages: 108-113 Pages count : 6 DOI: 10.1016/j.catcom.2017.09.001
Tags Aldehyde, Continuous flow reactor, Molecular hydrogen, Nitroarene, One-pot reductive amination, Supported copper catalyst
Authors Nuzhdin Alexey L. 1 , Artiukha Ekaterina A. 1 , Bukhtiyarova Galina A. 1 , Derevyannikova Elizaveta A. 1,2 , Bukhtiyarov Valerii I. 1,2
Affiliations
1 Boreskov Institute of Catalysis SB RAS, Lavrentieva Ave. 5, Novosibirsk 630090, Russia
2 Novosibirsk State University, Pirogova Str. 2, Novosibirsk 630090, Russia

Funding (1)

1 Federal Agency for Scientific Organizations 0303-2016-0006 (V.44.1.6)

Abstract: Supported copper catalysts were investigated for the one-pot reductive amination of aldehydes with nitroarenes in a continuous flow reactor. This process is considered advantageous compared to current traditional methods, which present several drawbacks, such as toxicity of reducing or alkylation agent, lack of monoalkylation selectivity and large amounts of waste produced. Various secondary amines were synthesized in good to excellent yields in the reactions of aliphatic aldehydes with nitroarenes using molecular hydrogen as a reducing agent. It was found that the yield of secondary amine depends on the rate of formation of intermediate imine.
Cite: Nuzhdin A.L. , Artiukha E.A. , Bukhtiyarova G.A. , Derevyannikova E.A. , Bukhtiyarov V.I.
Synthesis of Secondary Amines by Reductive Amination of Aldehydes with Nitroarenes over Supported Copper Catalysts in a Flow Reactor
Catalysis Communications. 2017. V.102. P.108-113. DOI: 10.1016/j.catcom.2017.09.001 publication_identifier_short.wos_identifier_type publication_identifier_short.scopus_identifier_type publication_identifier_short.rinz_identifier_type
Dates:
Submitted: Jun 20, 2017
Accepted: Sep 3, 2017
Published online: Sep 5, 2017
Published print: Dec 1, 2017
Identifiers:
publication_identifier.wos_identifier_type WOS:000413058800025
publication_identifier.scopus_identifier_type 2-s2.0-85029178266
publication_identifier.rinz_identifier_type 31039549
publication_identifier.accession_number_identifier_type 2017:1488910
publication_identifier.chemical_accession_number_identifier_type 167:431173
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