Comparative Estimation of the Selectivity Parameters for Monolith HPLC Columns with Organic Sorbents
Russian Journal of Physical Chemistry A
, E-ISSN: 1531-863X
||HPLC, monolith columns, porous polymers, 1-vinylimidazole, 4-vinylpyridine, model of linear solvation energy relationship
Yudina Yu. S.
Patrushev Yu. V.
Sidel’nikov V. N.
Boreskov Institute of Catalysis, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia
Novosibirsk State University, Novosibirsk, 630090 Russia
Monolith chromatographic columns are prepared for HPLC with sorbents based on 1-vinylimidazole and 4-vinylpyridine. A comparative estimation of column selectivity is performed using a model of the linear solvation energy relationship (LSER). Column polarity is shown to vary over a wide range by changing the content of 1-vinylimidazole and 4-vinylpyridine in the initial polymerization mixture. Examples are given of separation on the prepared columns.