Transformations of Acetophenone and Its Derivatives in Supercritical Solvent Isopropanol/CO2 in a Continuous Flow Reactor in the Presence of Alumina
Full article
| Общее |
Language:
Английский,
Genre:
Full article,
Status:
Published,
Source type:
Original
|
| Journal |
The Journal of Supercritical Fluids
ISSN: 0896-8446
, E-ISSN: 1872-8162
|
| Output data |
Year: 2012,
Volume: 70,
Pages: 35-39
Pages count
: 5
DOI:
10.1016/j.supflu.2012.05.012
|
| Tags |
Acetophenone, Alumina, Meerwein-Ponndorf-Verley reduction, Styrene, Supercritical CO 2, Supercritical isopropanol |
| Authors |
Sivcev V.P.
3
,
Volcho K.P.
2
,
Salakhutdinov N.F.
2
,
Anikeev V.I.
1
|
| Affiliations |
| 1 |
Boreskov Institute of Catalysis, Siberian Branch of the Russian Academy of Sciences, Prosp. Akad. Lavrent’eva 5, Novosibirsk 630090, Russian Federation
|
| 2 |
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Prosp. Akad. Lavrent’eva 9, Novosibirsk 630090, Russian Federation
|
| 3 |
Novosibirsk State University, Pirogova st. 2, Novosibirsk 630090, Russian Federation
|
|
Funding (1)
|
1
|
Russian Foundation for Basic Research
|
11-08-00171
|
Acetophenone and its derivatives undergo various transformations in binary supercritical solvent isopropanol/CO2 in a flow reactor in the presence of granulated Al2O3. Depending on the reaction temperature, respective secondary alcohols, or isopropyl ethers, or substituted styrenes are formed at contact times of ~4 min. Selectivity for the reaction products attains 96% at high conversion of initial compounds. It was shown that the nature of a substitute in ketone aromatic ring exerts primary effect both on the conversion of initial compounds and on stability of intermediates under reaction conditions, and thus affects the end product distribution.