Cytotoxic and Immunomodulating Properties of Gold Nanoparticles Full article
Journal |
Chemistry for Sustainable Development
ISSN: 1817-1818 |
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Output data | Year: 2013, Volume: 21, Number: 2, Pages: 169-178 Pages count : 10 | ||||||||
Tags | gold nanoparticles, toxicity, immunomodulating properties, primary and transformed cell cultures | ||||||||
Authors |
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Affiliations |
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Funding (2)
1 | Siberian Branch of the Russian Academy of Sciences | 9 |
2 | The Ministry of Education and Science of the Russian Federation | 8289 |
Abstract:
Results of the investigation of cytotoxic and immunomodulating properties of gold n anoparticles of
different sizes (12, 16, 22 and 35 nm) on primary and transformed cells in vitro are presented. Their localization
and distribution in cells are studied. It is established that gold nanoparticles are not toxic within concentration
range 0.066 µg/mL for all the cell cultures used, actively penetrate into the cell and get accumulated
inside the vacuoles of different sizes, selectively activate the anti-inflammatory immune response depending
on n anoparticle size and cell type.
Cite:
Kharkova M.V.
, Cherepanova A.V.
, Morozkin E.S.
, Zaporozhchenko I.A.
, Laktionov P.P.
, Strunov A.A.
, Kiseleva E.V.
, Tolstikova T.G.
, Shikina N.V.
, Ismagilov Z.R.
, Vlasov V.V.
Cytotoxic and Immunomodulating Properties of Gold Nanoparticles
Chemistry for Sustainable Development. 2013. V.21. N2. P.169-178. РИНЦ
Cytotoxic and Immunomodulating Properties of Gold Nanoparticles
Chemistry for Sustainable Development. 2013. V.21. N2. P.169-178. РИНЦ
ArticleLinkType.TRANSLATED_TO_ORIGINAL:
Харькова М.В.
, Черепанова А.В.
, Морозкин Е.С.
, Запорожченко И.А.
, Лактионов П.П.
, Струнов А.А.
, Киселева Е.В.
, Толстикова Т.Г.
, Шикина Н.В.
, Исмагилов З.Р.
, Власов В.В.
Цитотоксические и иммуномодулирующие свойства наночастиц золота
Химия в интересах устойчивого развития. 2013. Т.21. №2. С.179-188. RSCI РИНЦ
Цитотоксические и иммуномодулирующие свойства наночастиц золота
Химия в интересах устойчивого развития. 2013. Т.21. №2. С.179-188. RSCI РИНЦ
Dates:
Submitted: | Jul 26, 2012 |
Identifiers:
Elibrary | 30760300 |
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