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Cytotoxic and Immunomodulating Properties of Gold Nanoparticles Full article

Общее Language: Английский, Genre: Full article,
Status: Published, Source type: Translated
Journal Chemistry for Sustainable Development
ISSN: 1817-1818
Output data Year: 2013, Volume: 21, Number: 2, Pages: 169-178 Pages count : 10
Authors Kharkova M.V. 1 , Cherepanova A.V. 1 , Morozkin E.S. 1 , Zaporozhchenko I.A. 1 , Laktionov P.P. 1 , Strunov A.A. 2 , Kiseleva E.V. 2 , Tolstikova T.G. 4 , Shikina N.V. 3 , Ismagilov Z.R. 3 , Vlasov V.V. 1
Affiliations
1 Institute of Chemical Biology and Fundamental Medicine SB RAS
2 Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences
3 Boreskov Institute of Catalysis SB RAS
4 Vorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science

Funding (2)

1 Президиум СО РАН 9
2 The Ministry of Education and Science of the Russian Federation 8289

Abstract: Results of the investigation of cytotoxic and immunomodulating properties of gold n anoparticles of different sizes (12, 16, 22 and 35 nm) on primary and transformed cells in vitro are presented. Their localization and distribution in cells are studied. It is established that gold nanoparticles are not toxic within concentration range 0.066 µg/mL for all the cell cultures used, actively penetrate into the cell and get accumulated inside the vacuoles of different sizes, selectively activate the anti-inflammatory immune response depending on n anoparticle size and cell type.
Cite: Kharkova M.V. , Cherepanova A.V. , Morozkin E.S. , Zaporozhchenko I.A. , Laktionov P.P. , Strunov A.A. , Kiseleva E.V. , Tolstikova T.G. , Shikina N.V. , Ismagilov Z.R. , Vlasov V.V.
Cytotoxic and Immunomodulating Properties of Gold Nanoparticles
Chemistry for Sustainable Development. 2013. V.21. N2. P.169-178. publication_identifier_short.rinz_identifier_type
ArticleLinkType.TRANSLATED_TO_ORIGINAL: Харькова М.В. , Черепанова А.В. , Морозкин Е.С. , Запорожченко И.А. , Лактионов П.П. , Струнов А.А. , Киселева Е.В. , Толстикова Т.Г. , Шикина Н.В. , Исмагилов З.Р. , Власов В.В.
Цитотоксические и иммуномодулирующие свойства наночастиц золота
Химия в интересах устойчивого развития. 2013. Т.21. №2. С.179-188. publication_identifier_short.rsci_identifier_type publication_identifier_short.rinz_identifier_type
Identifiers:
publication_identifier.rinz_identifier_type 30760300