Design of the Surface of Particles in the Emulsion Polymerization of Methyl Methacrylate in the Presence of Carboxylated Dextran Derivatives Научная публикация
Журнал |
Polymer Science Series A
ISSN: 0965-545X , E-ISSN: 1555-6107 |
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Вых. Данные | Год: 2003, Том: 45, Номер: 4, Страницы: 380-385 Страниц : 6 | ||||
Ключевые слова | 4,4' azobis(4 cyanisovaleric acid); adjuvant; bovine serum albumin; carboxyethyldextran; carboxyl group; carboxymethyldextran; cholera toxin; dextran derivative; drug carrier; escherichia coli cholera like toxin; methacrylic acid; methyl ester; polymer; polysaccharide; stabilizing agent; unclassified drug; valeric acid derivative | ||||
Авторы |
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Организации |
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Реферат:
It was shown that carboxylated dextran derivatives used as polymer stabilizers can significantly accelerate the emulsion polymerization of methyl methacrylate initiated by 4,4'-azo-bis(4-cyanisovaleric acid). It was proposed that the process proceeds via the microemulsion mechanism. By varying the structure of a dextran derivative and its concentration in the reaction mixture, one can accomplish the targeted design of submicron monodisperse particles and can influence the structure of their surface. Using the microelectrophoresis method, it was established that the surface carboxyl groups located on polysaccharide chains exhibit an enhanced mobility. The adsorption and covalent binding of a protein by the surface of the obtained particles were studied, and their efficiency as adjuvant immunoreagent carriers was demonstrated.
Библиографическая ссылка:
Menʹshikova A.Y.
, Evseeva T.G.
, Chekina N.A.
, Skurkis Y.O.
, Ivanchev S.S.
Design of the Surface of Particles in the Emulsion Polymerization of Methyl Methacrylate in the Presence of Carboxylated Dextran Derivatives
Polymer Science Series A. 2003. V.45. N4. P.380-385. WOS Scopus РИНЦ
Design of the Surface of Particles in the Emulsion Polymerization of Methyl Methacrylate in the Presence of Carboxylated Dextran Derivatives
Polymer Science Series A. 2003. V.45. N4. P.380-385. WOS Scopus РИНЦ
Оригинальная версия:
Меньшикова А.Ю.
, Евсеева Т.Г.
, Чекина Н.А.
, Скуркис Ю.О.
, Иванчев С.С.
Формирование поверхности частиц при эмульсионной полимеризации метилметакрилата в присутствии карбоксилированных производных декстрана
Высокомолекулярные соединения. Серия А. 2003. Т.45. №4. С.623-630. Scopus РИНЦ
Формирование поверхности частиц при эмульсионной полимеризации метилметакрилата в присутствии карбоксилированных производных декстрана
Высокомолекулярные соединения. Серия А. 2003. Т.45. №4. С.623-630. Scopus РИНЦ
Даты:
Опубликована в печати: | 1 апр. 2003 г. |
Идентификаторы БД:
Web of science | WOS:000183022500011 |
Scopus | 2-s2.0-0038173433 |
РИНЦ | 13442917 |