Kinetic Model of Receptor-Mediated Adhesion of Cells to a Functionalized Supported Lipid Bilayer Научная публикация
Журнал |
Chemical Physics Letters
ISSN: 0009-2614 , E-ISSN: 1873-4448 |
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Вых. Данные | Год: 2007, Том: 448, Номер: 4-6, Страницы: 268-272 Страниц : 5 DOI: 10.1016/j.cplett.2007.10.010 | ||||
Ключевые слова | Bonding; Diffusion; Ligands; Lipid bilayers; Reaction kinetics | ||||
Авторы |
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Организации |
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Информация о финансировании (3)
1 | Swedish Research Council | |
2 | Stiftelsen för strategisk forskning | |
3 | European Commission | 505868 FP6-2002-NMP-1 STREP NANOCUES |
Реферат:
We present a kinetic model describing adhesion of cells to a supported lipid bilayer due to formation of bonds between cellular receptors and ligands (e.g., peptides or proteins) attached to the bilayer. The model implies a power-law dependence of the adhesion rate on the ligand concentration and takes into account ligand diffusion and association with already adhered cells. For a time interval longer than the sedimentation time, it predicts a sigmoidal dependence of the population of adhered cells on the initial ligand concentration. This feature becomes less pronounced with increasing rate of ligand association with adhered cells. The results obtained are used to interpret recent experiments with rat adult neural progenitor cells.
Библиографическая ссылка:
Zhdanov V.P.
, Kasemo B.
Kinetic Model of Receptor-Mediated Adhesion of Cells to a Functionalized Supported Lipid Bilayer
Chemical Physics Letters. 2007. V.448. N4-6. P.268-272. DOI: 10.1016/j.cplett.2007.10.010 WOS Scopus РИНЦ
Kinetic Model of Receptor-Mediated Adhesion of Cells to a Functionalized Supported Lipid Bilayer
Chemical Physics Letters. 2007. V.448. N4-6. P.268-272. DOI: 10.1016/j.cplett.2007.10.010 WOS Scopus РИНЦ
Даты:
Поступила в редакцию: | 27 июн. 2007 г. |
Принята к публикации: | 4 окт. 2007 г. |
Опубликована online: | 9 окт. 2007 г. |
Опубликована в печати: | 14 нояб. 2007 г. |
Идентификаторы БД:
Web of science | WOS:000251408300024 |
Scopus | 2-s2.0-35648979436 |
РИНЦ | 13549614 |
Chemical Abstracts | 2007:1254248 |
Chemical Abstracts (print) | 148:95035 |
OpenAlex | W2041265455 |
Цитирование в БД:
Пока нет цитирований