Enhancement of Protein Adsorption Induced by Surface Roughness Письма в редакцию
Журнал |
Langmuir
ISSN: 0743-7463 , E-ISSN: 1520-5827 |
||||
---|---|---|---|---|---|
Вых. Данные | Год: 2006, Том: 22, Номер: 26, Страницы: 10885-10888 Страниц : 4 DOI: 10.1021/la0621923 | ||||
Ключевые слова | Computer simulation; Crystal atomic structure; Ellipsometry; Quartz; Surface roughness | ||||
Авторы |
|
||||
Организации |
|
Информация о финансировании (2)
1 | European Commission | 505868 FP6-2002-NMP-1 STREP NANOCUES |
2 | Danish National Research Foundation | 2052-01-0006 |
Реферат:
Using quartz crystal microbalance with dissipation and ellipsometry, we show that during adsorption of fibrinogen on evaporated tantalum films the saturation uptake increases with increasing root-mean-square roughness (from 2.0 to 32.9 nm) beyond the accompanying increase in surface area. This increase is attributed to a change in the geometrical arrangement of the fibrinogen molecules on the surface. For comparison, the adsorption of a nearly globular protein, bovine serum albumin, was studied as well. In this case, the adsorption was less influenced by the roughness. Simple Monte Carlo simulations taking into account surface roughness and the anisotropic shape of fibrinogen reproduce the experimentally observed trend.
Библиографическая ссылка:
Rechendorff K.
, Hovgaard M.B.
, Foss M.
, Zhdanov V.P.
, Besenbacher F.
Enhancement of Protein Adsorption Induced by Surface Roughness
Langmuir. 2006. V.22. N26. P.10885-10888. DOI: 10.1021/la0621923 WOS Scopus РИНЦ
Enhancement of Protein Adsorption Induced by Surface Roughness
Langmuir. 2006. V.22. N26. P.10885-10888. DOI: 10.1021/la0621923 WOS Scopus РИНЦ
Даты:
Поступила в редакцию: | 26 июл. 2006 г. |
Принята к публикации: | 2 нояб. 2006 г. |
Опубликована online: | 15 нояб. 2006 г. |
Опубликована в печати: | 1 дек. 2006 г. |
Идентификаторы БД:
Web of science | WOS:000242771200007 |
Scopus | 2-s2.0-33846392619 |
РИНЦ | 13520675 |
Chemical Abstracts | 2006:1194788 |
Chemical Abstracts (print) | 146:96017 |
OpenAlex | W2036374139 |