Adsorption of Proteins on a Lipid Bilayer Научная публикация
Журнал |
European Biophysics Journal with Biophysics Letters
ISSN: 0175-7571 , E-ISSN: 1432-1017 |
||||
---|---|---|---|---|---|
Вых. Данные | Год: 2010, Том: 39, Номер: 11, Страницы: 1477-1482 Страниц : 6 DOI: 10.1007/s00249-010-0604-0 | ||||
Ключевые слова | Adsorption energy, Electrostatic interactions, Lipids, Poisson-Boltzmann equation, Proteins | ||||
Авторы |
|
||||
Организации |
|
Реферат:
In our analysis of protein adsorption on a lipid bilayer, the protein surface is considered to contain one or a few charged spots, and the bilayer contains a significant amount of lipids with oppositely charged head groups. After adsorption, a folded protein is assumed to change its shape slightly due to the electrostatic attraction, so that one of the spots forms a flat contact with the oppositely charged lipid heads of the lipid bilayer. With realistic parameters, this model predicts that the contribution of electrostatic interactions to the protein adsorption energy per charged amino acid–lipid pair is 16–25 kJ/mol. Thus, a few (four or five) pairs is sufficient for irreversible adsorption.
Библиографическая ссылка:
Zhdanov V.P.
, Kasemo B.
Adsorption of Proteins on a Lipid Bilayer
European Biophysics Journal with Biophysics Letters. 2010. V.39. N11. P.1477-1482. DOI: 10.1007/s00249-010-0604-0 WOS Scopus РИНЦ
Adsorption of Proteins on a Lipid Bilayer
European Biophysics Journal with Biophysics Letters. 2010. V.39. N11. P.1477-1482. DOI: 10.1007/s00249-010-0604-0 WOS Scopus РИНЦ
Даты:
Поступила в редакцию: | 11 нояб. 2009 г. |
Принята к публикации: | 24 мар. 2010 г. |
Опубликована online: | 13 апр. 2010 г. |
Опубликована в печати: | 1 окт. 2010 г. |
Идентификаторы БД:
Web of science | WOS:000282095700002 |
Scopus | 2-s2.0-77957715097 |
РИНЦ | 22041869 |
Chemical Abstracts | 2010:1204479 |
Chemical Abstracts (print) | 157:156339 |
OpenAlex | W1997273795 |