Polymer Hydrogels with the Memory Effect for Immobilization of Drugs | Sciact - CRIS-система Института катализа

Polymer Hydrogels with the Memory Effect for Immobilization of Drugs Научная публикация

Общее

Язык: Английский, Жанр: Статья (Full article),
Статус опубликования: Опубликована, Оригинальность: Переводная

Журнал

Polymer Science Series B
ISSN: 1560-0904 , E-ISSN: 1531-8583

Вых. Данные

Год: 2014, Том: 56, Номер: 6, Страницы: 863-870 Страниц : 8 DOI: 10.1134/S1560090414060128

Авторы

Primachenko O.N.

¹ , Marinenko E.A.

¹ , Ivanchev S.S.

Организации

1	Санкт-Петербургский филиал Института катализа им. Г.К. Борескова СО РАН

Medicinal soft contact lenses are synthesized via the template method from hydrogels with the mem ory effect (imprinted hydrogels) on the basis of copolymers of 2hydroxyethyl methacrylate and functional anionic and cationic monomers with the use of cefepime or diclofenac as a template. It is shown that the mem ory effect appears as an increase in the levels of sorption of cefepime and diclofenac by the imprinted hydrogels relative to those of conventional hydrogels with the same chemical compositions. The effect of selective sorption of diclofenac by medicinal soft contact lenses based on imprinted hydrogels during their saturation from the drug combination diclofenac–cefepime is observed for the first time. It is found that the release of diclofenac from medicinal soft contact lenses based on imprinted hydrogels decelerates and that the release of cefepime strongly accelerates if the combination of diclofenac and cefepime is used during hydrogel saturation.

Primachenko O.N. , Marinenko E.A. , Ivanchev S.S.
Polymer Hydrogels with the Memory Effect for Immobilization of Drugs
Polymer Science Series B. 2014. V.56. N6. P.863-870. DOI: 10.1134/S1560090414060128 WOS Scopus РИНЦ AN: 2014:2166188

Примаченко О.Н. , Мариненко Е.А. , Иванчев С.С.
Полимерные гидрогели для иммобилизации лекарственных веществ, обладающие эффектом памяти
Высокомолекулярные соединения. Серия Б. 2014. Т.56. №6. С.552-561. РИНЦ

Поступила в редакцию:	12 мая 2014 г.
Опубликована в печати:	1 нояб. 2014 г.
Опубликована online:	24 дек. 2014 г.

Chemical Abstracts	2014:2166188
Web of science	WOS:000346900800019
Scopus	2-s2.0-84919922356
РИНЦ	24024103