Inhibition of the Receptor-Mediated Virion Attachment to a Lipid Membrane Full article
Journal |
Central European Journal of Physics
ISSN: 1895-1082 , E-ISSN: 1644-3608 |
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Output data | Year: 2012, Volume: 10, Number: 5, Pages: 1210-1215 Pages count : 6 DOI: 10.2478/s11534-012-0119-7 | ||||
Tags | antibody therapeutics, mean-field kinetic equations, neutralization, viral entry, virology | ||||
Authors |
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Affiliations |
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Funding (1)
1 | Swedish Research Council | 2010-5063 |
Abstract:
The forefront of the anti-viral defence is sometimes aimed at virion attachment to a host membrane. This step or, more specifically, virion contacts with cellular membrane receptors (or, e.g., glycolipids) can be inhibited by antibodies (or specially chosen or designed compounds) via their association with virions. In this case, the full-scale attachment of virions to a host membrane occurs via a subtle interplay of the formation and rupture of multiple virion-inhibitor and virion-receptor bonds. We present a kinetic model describing this interplay and illustrating general trends in the process under consideration.
Cite:
Zhdanov V.P.
Inhibition of the Receptor-Mediated Virion Attachment to a Lipid Membrane
Central European Journal of Physics. 2012.
V.10. N5. P.1210-1215. DOI: 10.2478/s11534-012-0119-7
WOS
Scopus
РИНЦ
Inhibition of the Receptor-Mediated Virion Attachment to a Lipid Membrane
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Files:
Full text from publisher
Dates:
Submitted: | Jun 5, 2012 |
Accepted: | Aug 13, 2012 |
Published print: | Oct 1, 2012 |
Published online: | Nov 21, 2012 |
Identifiers:
Web of science | WOS:000311496400023 |
Scopus | 2-s2.0-84870359833 |
Elibrary | 20494251 |
Chemical Abstracts | 2012:1727207 |
Chemical Abstracts (print) | 158:463955 |
OpenAlex | W2070093060 |