Amplification of Kinetic Oscillations in Gene Expression Full article
Journal |
Journal of Experimental and Theoretical Physics Letters (JETP Letters)
ISSN: 0021-3640 , E-ISSN: 1090-6487 |
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Output data | Year: 2008, Volume: 88, Number: 4, Pages: 281-285 Pages count : 5 DOI: 10.1134/S0021364008160133 | ||||
Tags | PROTEIN EXPRESSION; MESSENGER-RNA; TRANSCRIPTION; DIFFUSION | ||||
Authors |
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Affiliations |
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Funding (1)
1 | Swedish Research Council |
Abstract:
Because of the feedbacks between the DNA transcription and mRNA translation, the gene expression in cells
may exhibit bistability and oscillations. The deterministic and stochastic calculations presented illustrate how
the bistable kinetics of expression of one gene in a cell can be influenced by the kinetic oscillations in the
expression of another gene. Due to stability of the states of the bistable kinetics of gene 1 and the relatively
small difference between the maximum and minimum protein amounts during the oscillations of gene 2, the
induced oscillations of gene 1 are found to typically be related either to the low- or high-reactive state of this
gene. The quality of the induced oscillations may be appreciably better than that of the inducing oscillations.
This means that gene 1 can serve as an amplifier of the kinetic oscillations of gene 2.
Cite:
Zhdanov V.P.
Amplification of Kinetic Oscillations in Gene Expression
Journal of Experimental and Theoretical Physics Letters (JETP Letters). 2008. V.88. N4. P.281-285. DOI: 10.1134/S0021364008160133 WOS Scopus РИНЦ
Amplification of Kinetic Oscillations in Gene Expression
Journal of Experimental and Theoretical Physics Letters (JETP Letters). 2008. V.88. N4. P.281-285. DOI: 10.1134/S0021364008160133 WOS Scopus РИНЦ
Original:
Zhdanov V.P.
Amplification of Kinetic Oscillations in Gene Expression
Письма в Журнал экспериментальной и теоретической физики. 2008. V.88. N3-4. P.321-325. RSCI РИНЦ
Amplification of Kinetic Oscillations in Gene Expression
Письма в Журнал экспериментальной и теоретической физики. 2008. V.88. N3-4. P.321-325. RSCI РИНЦ
Dates:
Submitted: | May 7, 2008 |
Accepted: | Jun 7, 2008 |
Published print: | Aug 25, 2008 |
Published online: | Feb 5, 2009 |
Identifiers:
Web of science | WOS:000262832300013 |
Scopus | 2-s2.0-59749094909 |
Elibrary | 13567605 |
Chemical Abstracts | 2008:1388883 |
Chemical Abstracts (print) | 150:160842 |
OpenAlex | W2051910744 |