Deracemization of Amino Acids by Partial Sublimation and via Homochiral Self-Organization Full article
Journal |
Origins of Life and Evolution of Biospheres
ISSN: 0169-6149 , E-ISSN: 1573-0875 |
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Output data | Year: 2013, Volume: 43, Pages: 129-135 Pages count : 7 DOI: 10.1007/s11084-013-9333-6 | ||||
Tags | Amino acid, Deracemization, Enantioenrichment, Homochirality, Self-organization, Sublimation | ||||
Authors |
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Abstract:
Deracemization of a 50/50 mixture of enantiomers of aliphatic amino acids (Ala, Leu, Pro, Val) can be achieved by a simple sublimation of a pre-solubilized solid mixture of the racemates with a huge amount of a less-volatile optically active amino acid (Asn, Asp, Glu, Ser, Thr). The choice of chirality correlates with the handedness of the enantiopure amino acids—Asn, Asp, Glu, Ser, and Thr. The deracemization, enantioenrichment and enantiodepletion observed in these experiments clearly demonstrate the preferential homochiral interactions and a tendency of natural amino acids to homochiral self-organization. These data may contribute toward an ultimate understanding of the pathways by which prebiological homochirality might have emerged.
Cite:
Tarasevych A.V.
, Sorochinskij A.E.
, Kukharʹ V.P.
, Guillemin J-C.
Deracemization of Amino Acids by Partial Sublimation and via Homochiral Self-Organization
Origins of Life and Evolution of Biospheres. 2013. V.43. P.129-135. DOI: 10.1007/s11084-013-9333-6 WOS Scopus РИНЦ
Deracemization of Amino Acids by Partial Sublimation and via Homochiral Self-Organization
Origins of Life and Evolution of Biospheres. 2013. V.43. P.129-135. DOI: 10.1007/s11084-013-9333-6 WOS Scopus РИНЦ
Dates:
Submitted: | Feb 25, 2013 |
Published print: | Apr 1, 2013 |
Accepted: | Apr 24, 2013 |
Published online: | May 21, 2013 |
Identifiers:
Web of science | WOS:000320364700005 |
Scopus | 2-s2.0-84878797487 |
Elibrary | 20522658 |
Chemical Abstracts | 2013:936555 |
Chemical Abstracts (print) | 160:440226 |
OpenAlex | W2122772220 |