Hydride Transfer Reactions of 5-(2-alkohybenzylidene) Barbituric Acids: Synthesis of 2,4,6-trioxoperhydropyrimidine-5-spiro-3′-chromanes Full article
Journal |
Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416 |
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Output data | Year: 2017, Volume: 73, Number: 5, Pages: 542-549 Pages count : 8 DOI: 10.1016/j.tet.2016.12.045 | ||||||||||
Tags | 5-(2-Alkoxyphenylmethylene)-barbituric acids; 1,5-Hydride shift; Thermal isomerization; T-reaction; Trioxoperhydropyrimidine-5-spiro-3′-chromane | ||||||||||
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Abstract:
The thermal cyclization of 5-(2-phenoxymethylphenyl-methylenbe)barbituric acid and its derivatives affords
2,4,6-trioxoperhydropyrimidine-5-spiro-3′-chromanes. The reactions require no catalysts and proceed at temperatures from 118 to 240 °C depending on the substrate activity. These cyclization reactions are analogous to T-reactions of tertiary amines involving the hydride transfer.
Cite:
Krasnov K.A.
, Dorovatovskii P.V.
, Zubavichus Y.V.
, Timofeeva T.V.
, Khrustalev V.N.
Hydride Transfer Reactions of 5-(2-alkohybenzylidene) Barbituric Acids: Synthesis of 2,4,6-trioxoperhydropyrimidine-5-spiro-3′-chromanes
Tetrahedron. 2017. V.73. N5. P.542-549. DOI: 10.1016/j.tet.2016.12.045 WOS Scopus РИНЦ
Hydride Transfer Reactions of 5-(2-alkohybenzylidene) Barbituric Acids: Synthesis of 2,4,6-trioxoperhydropyrimidine-5-spiro-3′-chromanes
Tetrahedron. 2017. V.73. N5. P.542-549. DOI: 10.1016/j.tet.2016.12.045 WOS Scopus РИНЦ
Files:
Full text from publisher
Dates:
Submitted: | Sep 15, 2016 |
Accepted: | Dec 19, 2016 |
Published online: | Dec 23, 2016 |
Published print: | Feb 2, 2017 |
Identifiers:
Web of science | WOS:000392888300014 |
Scopus | 2-s2.0-85008686883 |
Elibrary | 29468129 |
Chemical Abstracts | 2017:10040 |
Chemical Abstracts (print) | 166:144953 |
OpenAlex | W2561304846 |