Hydrogenation of 1-Ethyl-2-Nitromethylenepyrrolidine to 1-Ethyl-2-Aminomethylpyrrolidine over Pd/C Full article
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Kinetics and Catalysis
ISSN: 0023-1584 , E-ISSN: 1608-3210 |
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| Output data | Year: 1998, Volume: 39, Number: 2, Pages: 177-181 Pages count : 5 | ||
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Abstract:
The reaction pathways for the conversion of 1-ethyl-2-nitromethylenepyrrolidine (ENMP) during the liquid-phase hydrogenation over Pd/C are studied and the composition of the reaction products formed is determined. The effects of a solvent and the acidity of a medium on the reaction rates and selectivity with respect to 1-ethyl-2-aminomethylpyrrolidine (EAMP) are studied. It is shown that EAMP which creates an alkaline medium in the reaction solution is the catalyst of a side reaction of the ENMP conversion. A byproduct, 1-ethylpyrrolidone, is found to be formed via hydrolysis of ENMP by the mechanism of specific acid-base catalysis. Approaches to improve the selectivity of ENMP hydrogenation are proposed.
Cite:
Simakova I.L.
, Golovin A.V.
, Semikolenov V.A.
Hydrogenation of 1-Ethyl-2-Nitromethylenepyrrolidine to 1-Ethyl-2-Aminomethylpyrrolidine over Pd/C
Kinetics and Catalysis. 1998. V.39. N2. P.177-181. WOS Scopus РИНЦ ANCAN
Hydrogenation of 1-Ethyl-2-Nitromethylenepyrrolidine to 1-Ethyl-2-Aminomethylpyrrolidine over Pd/C
Kinetics and Catalysis. 1998. V.39. N2. P.177-181. WOS Scopus РИНЦ ANCAN
Original:
Симакова И.Л.
, Головин А.В.
, Семиколенов В.А.
Гидрирование 1-этил-2-нитрометиленпирролидина в 1-этил-2-аминометилпирролидин на Pd/C
Кинетика и катализ. 1998. Т.39. №2. С.193-197. РИНЦ
Гидрирование 1-этил-2-нитрометиленпирролидина в 1-этил-2-аминометилпирролидин на Pd/C
Кинетика и катализ. 1998. Т.39. №2. С.193-197. РИНЦ
Dates:
| Submitted: | Apr 29, 1996 |
Identifiers:
| Web of science: | WOS:000073168400006 |
| Scopus: | 2-s2.0-1542467580 |
| Elibrary: | 13286590 |
| Chemical Abstracts: | 1998:265537 |
| Chemical Abstracts (print): | 129:4365 |