Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic? Full article
| Journal |
Journal of Experimental and Theoretical Physics Letters (JETP Letters)
ISSN: 0021-3640 , E-ISSN: 1090-6487 |
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| Output data | Year: 2011, Volume: 93, Number: 1, Pages: 41-45 Pages count : 5 DOI: 10.1134/S0021364011010097 | ||||
| Tags | Monte Carlo JETP Letter Regulatory Site Monte Carlo Calculation Genetic Network | ||||
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Abstract:
Complex mRNA-protein networks with distributed regulation of gene transcription are often mimicked by random Boolean networks. According to this mapping, the gene-expression kinetics are expected to depend strongly on the network connectivity, m. Specifically, the kinetics are predicted to be oscillatory or chaotic for m > 2. We analyze this problem in more detail by using an accurate model explicitly describing the mRNA-protein interplay with randomly organized transcriptional regulation. Contrary to the expectations, our mean-field calculations and Monte Carlo simulations performed for m = 1, 2 and 4 show that oscillations and chaos are lacking irrespective of m.
Cite:
Zhdanov V.P.
Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic?
Journal of Experimental and Theoretical Physics Letters (JETP Letters). 2011. V.93. N1. P.41-45. DOI: 10.1134/S0021364011010097 WOS Scopus РИНЦ ANCAN OpenAlex
Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic?
Journal of Experimental and Theoretical Physics Letters (JETP Letters). 2011. V.93. N1. P.41-45. DOI: 10.1134/S0021364011010097 WOS Scopus РИНЦ ANCAN OpenAlex
Original:
Zhdanov V.P.
Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic?
Письма в Журнал экспериментальной и теоретической физики. 2011. V.93. N1. P.43-47. РИНЦ
Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic?
Письма в Журнал экспериментальной и теоретической физики. 2011. V.93. N1. P.43-47. РИНЦ
Dates:
| Submitted: | Nov 16, 2010 |
| Published print: | Mar 1, 2011 |
| Published online: | Mar 24, 2011 |
Identifiers:
| Web of science: | WOS:000288711700009 |
| Scopus: | 2-s2.0-79953004697 |
| Elibrary: | 16995099 |
| Chemical Abstracts: | 2011:364419 |
| Chemical Abstracts (print): | 155:32613 |
| OpenAlex: | W1991349985 |