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Synthesis of Unsaturated Secondary Amines by Direct Reductive Amination of Aliphatic Aldehydes with Nitroarenes over Au/Al2O3 Catalyst in a Continuous Flow Mode Научная публикация

Журнал RSC Advances
ISSN: 2046-2069
Вых. Данные Год: 2016, Том: 6, Номер: 91, Страницы: 88366 - 88372 Страниц : 7 DOI: 10.1039/C6RA20904A
Ключевые слова ONE-POT; NITRO ARYLS; RECOVERABLE CATALYST; CARBONYL-COMPOUNDS; MILD CONDITIONS; GREEN SYNTHESIS; SUPPORTED GOLD; HYDROGENATION; MONOALKYLATION; NANOPARTICLES
Авторы Nuzhdin A.L. 1 , Artyukha E.A. 1,2 , Bukhtiyarova G.A. 1 , Zaytsev S.Yu. 3 , Plyusnin P.E. 2,3 , Shubin Yu.V. 2,3 , Bukhtiyarov V.I. 1,2
Организации
1 Boreskov Institute of Catalysis, SB RAS, Lavrentieva Ave. 5, Novosibirsk, 630090, Russia
2 Novosibirsk State University, Pirogova Str. 2, Novosibirsk, 630090 Russia
3 Nikolaev Institute of Inorganic Chemistry, SB RAS, Lavrentieva Ave. 3, Novosibirsk, 630090 Russia

Информация о финансировании (1)

1 Федеральное агентство научных организаций России V.45.3.7.

Реферат: A series of unsaturated secondary amines was successfully synthesized by direct reductive amination of aliphatic aldehydes with nitroarenes over a 2.5% Au/Al2O3 catalyst in a continuous flow reactor using molecular hydrogen as a reducing agent. In most cases, the targeted secondary amines were obtained in good to excellent yields. Interestingly, the hydrogenation of C]C group is practically absent in both initial aldehydes and secondary amines under the reaction conditions. It was found that the introduction of electron-donating substituents in the para- and meta-position of nitrobenzenes increased the yield of secondary amine, while in the case of nitrobenzenes with electron-withdrawing substituents or electron-donating substituents in the ortho-position a decrease in the yield of the target product was observed.
Библиографическая ссылка: Nuzhdin A.L. , Artyukha E.A. , Bukhtiyarova G.A. , Zaytsev S.Y. , Plyusnin P.E. , Shubin Y.V. , Bukhtiyarov V.I.
Synthesis of Unsaturated Secondary Amines by Direct Reductive Amination of Aliphatic Aldehydes with Nitroarenes over Au/Al2O3 Catalyst in a Continuous Flow Mode
RSC Advances. 2016. V.6. N91. P.88366 - 88372. DOI: 10.1039/C6RA20904A WOS Scopus РИНЦ CAPlus OpenAlex
Даты:
Поступила в редакцию: 19 авг. 2016 г.
Принята к публикации: 1 сент. 2016 г.
Опубликована online: 2 сент. 2016 г.
Идентификаторы БД:
Web of science: WOS:000384571800064
Scopus: 2-s2.0-84988420330
РИНЦ: 27572522
Chemical Abstracts: 2016:1460762
OpenAlex: W2515791288
Цитирование в БД:
БД Цитирований
Web of science 17
Scopus 19
РИНЦ 17
OpenAlex 18
Альметрики: