Kinetics of Enzyme-Mediated Hydrolysis of Lipid Vesicles Научная публикация
| Журнал |
Chemical Physics Letters
ISSN: 0009-2614 , E-ISSN: 1873-4448 |
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| Вых. Данные | Год: 2016, Том: 663, Страницы: 51-56 Страниц : 6 DOI: 10.1016/j.cplett.2016.09.018 | ||||
| Ключевые слова | Enzymatic catalysis, Lipid membranes, Mean-field kinetic equations, Monte Carlo simulations, Stochastic kinetics | ||||
| Авторы |
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| Организации |
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Информация о финансировании (1)
| 1 | Swedish Research Council | 2013-7421 |
Реферат:
Membrane enzymatic reactions can now be experimentally studied at the level of single sub-100 nm lipid vesicles. To interpret such experiments, we scrutinize theoretically various aspects of the hydrolysis of vesicles by single enzyme molecules and enzyme (e.g., PLA2) supplied with the constant rate. Using the mean-field kinetic model, we illustrate the shape of the corresponding kinetics and the dependence of the time scale of the reaction on the vesicle radius. Stochastic effects are illustrated as well. In addition, we discuss the likely mechanisms of the reaction-induced pore formation and bilayer rupture
Библиографическая ссылка:
Zhdanov V.P.
, Agnarsson B.
, Höök F.
Kinetics of Enzyme-Mediated Hydrolysis of Lipid Vesicles
Chemical Physics Letters. 2016. V.663. P.51-56. DOI: 10.1016/j.cplett.2016.09.018 WOS Scopus РИНЦ CAPlusCA OpenAlex
Kinetics of Enzyme-Mediated Hydrolysis of Lipid Vesicles
Chemical Physics Letters. 2016. V.663. P.51-56. DOI: 10.1016/j.cplett.2016.09.018 WOS Scopus РИНЦ CAPlusCA OpenAlex
Даты:
| Поступила в редакцию: | 28 июл. 2016 г. |
| Принята к публикации: | 10 сент. 2016 г. |
| Опубликована online: | 15 сент. 2016 г. |
| Опубликована в печати: | 16 окт. 2016 г. |
Идентификаторы БД:
| Web of science: | WOS:000387193100009 |
| Scopus: | 2-s2.0-84988822552 |
| РИНЦ: | 27569326 |
| Chemical Abstracts: | 2016:1588504 |
| Chemical Abstracts (print): | 165:413440 |
| OpenAlex: | W2519720796 |