2D Mapping of NMR Signal Enhancement and Relaxation for Heterogeneously Hyperpolarized Propane Gas | Sciact - CRIS-system of Boreskov Institute of Catalysis

2D Mapping of NMR Signal Enhancement and Relaxation for Heterogeneously Hyperpolarized Propane Gas Full article

Journal

The Journal of Physical Chemistry C
ISSN: 1932-7447 , E-ISSN: 1932-7455

Output data

Year: 2017, Volume: 121, Number: 18, Pages: 10038-10046 Pages count : 9 DOI: 10.1021/acs.jpcc.7b02506

Tags

Catalysts; Contrast media; Gas mixtures; Hydrogen; Magnetic resonance imaging; Mapping; Nuclear magnetic resonance; Polarization; Porous materials; Propane; Propylene; Rhodium compounds; Titanium compounds; X ray photoelectron spectroscopy

Authors

Barskiy Danila A. ¹ , Kovtunov Kirill V. ^2,3 , Gerasimov Evgeny Y. ^3,4 , Phipps M.Anthony ¹ , Salnikov Oleg G. ^2,3 , Coffey Aaron M. ¹ , Kovtunova Larisa M. ^3,4 , Prosvirin Igor P. ^3,4 , Bukhtiyarov Valerii I. ^3,4 , Koptyug Igor V. ^2,3 , Chekmenev Eduard Y. ^1,5,6

Affiliations

1	Vanderbilt University Institute of Imaging Science (VUIIS), Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States
2	International Tomography Center SB RAS, Novosibirsk 630090, Russia
3	Novosibirsk State University, Novosibirsk 630090, Russia
4	Boreskov Institute of Catalysis SB RAS, Novosibirsk 630090, Russia
5	Department of Biomedical Engineering, Department of Physics, Vanderbilt-Ingram Cancer Center (VICC), Nashville, Tennessee 37232, United States
6	Russian Academy of Sciences, 19991 Moscow, Russia

Funding (11)

1	Russian Science Foundation	14-23-00146
2	Russian Foundation for Basic Research	16-03-00407
3	The Ministry of Education and Science of the Russian Federation	МК-4498.2016.3
4	National Institutes of Health	1R21EB018014
5	National Institutes of Health	1R21EB020323
6	National Science Foundation	CHE-1416268
7	United States Department of Defense	W81XWH-12-1-0159/BC112431
8	United States Department of Defense	W81XWH-15-1-0271
9	National Science Foundation	CHE-1416432
10	United States Department of Defense	W81XWH-15-1-0272
11	Federal Agency for Scientific Organizations	V.44.1.8. (0333-2016-0001)

Hyperpolarized (HP) propane is a promising contrast agent for magnetic resonance imaging (MRI) of lungs and for studying porous media. The parahydrogen-induced polarization (PHIP) technique is a convenient approach to produce pure propane gas with enhanced proton polarization, when hydrogenation of propylene with parahydrogen is performed over heterogeneous catalysts. Here, we present a new approach of multidimensional mapping of the efficiency of pairwise parahydrogen addition using PHIP-echo pulse sequence. We use this approach to study the performance of three model heterogeneous Rh/TiO2 catalysts in the production of HP propane gas. The three catalysts with 1.0, 13.7, and 23.2 wt % of supported rhodium nanoparticles have been characterized by X-ray photoelectron spectroscopy (XPS) and high resolution transition electron microscopy (HRTEM). By varying the fractions of parahydrogen and propylene in the reactant mixture as well as the gas mixture pressure, 2D maps of PHIP-echo NMR signal and 2D maps of HP propane NMR signal enhancement were obtained. These maps clearly indicate that lower metal coverage results in more efficient pairwise hydrogen addition, producing greater levels of proton polarization of propane gas. The presented method can be extended to multidimensional characterization of the influence of other key parameters of PHIP reaction process including temperature or addition of an inert carrier gas. A 2D T1 relaxation map of propane at 9.4 T is also reported as a function of propane fraction (in the mixture with hydrogen) and gas mixture pressure.

Barskiy D.A. , Kovtunov K.V. , Gerasimov E.Y. , Phipps M.A. , Salnikov O.G. , Coffey A.M. , Kovtunova L.M. , Prosvirin I.P. , Bukhtiyarov V.I. , Koptyug I.V. , Chekmenev E.Y.
2D Mapping of NMR Signal Enhancement and Relaxation for Heterogeneously Hyperpolarized Propane Gas

The Journal of Physical Chemistry C. 2017. V.121. N18. P.10038-10046. DOI: 10.1021/acs.jpcc.7b02506 WOS Scopus РИНЦ ANCAN OpenAlex

Full text from publisher

Submitted:	Mar 16, 2017
Accepted:	Apr 18, 2017
Published online:	Apr 18, 2017
Published print:	May 11, 2017

Web of science:	WOS:000401402100042
Scopus:	2-s2.0-85020414755
Elibrary:	35481015
Chemical Abstracts:	2017:629630
Chemical Abstracts (print):	166:459712
OpenAlex:	W2605856693

DB	Citing
Web of science	31
Scopus	32
Elibrary	30
OpenAlex	35