Pulling-Induced Rupture of Ligand-Receptor Bonds Between a Spherically Shaped Bionanoparticle and the Support | Sciact - CRIS-система Института катализа

Pulling-Induced Rupture of Ligand-Receptor Bonds Between a Spherically Shaped Bionanoparticle and the Support Научная публикация

Журнал

Physics Letters A
ISSN: 0375-9601

Вых. Данные

Год: 2018, Том: 382, Номер: 15, Страницы: 1052-1057 Страниц : 6 DOI: 10.1016/j.physleta.2018.02.010

Ключевые слова

Nanoscience, Force spectroscopy, Spherical nanoparticles, Bond rupture

Авторы

Zhdanov Vladimir P. ^1,2

Организации

1	Section of Biological Physics, Department of Physics, Chalmers University of Technology, Göteborg, Sweden
2	Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk, Russia

Информация о финансировании (1)

Федеральное агентство научных организаций России

0303-2016-0001

Contacts of biological or biologically-inspired spherically shaped nanoparticles (e.g., virions or lipid nanoparticles used for intracellular RNA delivery) with a lipid membrane of cells are often mediated by multiple relatively weak ligand-receptor bonds. Such contacts can be studied at a supported lipid bilayer. The rupture of bonds can be scrutinized by using force spectroscopy. Bearing a supported lipid bilayer in mind, the author shows analytically that the corresponding dependence of the force on the nanoparticle displacement and the effect of the force on the bond-rupture activation energy are qualitatively different compared to what is predicted by the conventional Bell approximation.

Zhdanov V.P.
Pulling-Induced Rupture of Ligand-Receptor Bonds Between a Spherically Shaped Bionanoparticle and the Support
Physics Letters A. 2018. V.382. N15. P.1052-1057. DOI: 10.1016/j.physleta.2018.02.010 WOS Scopus РИНЦ CAPlus OpenAlex

Поступила в редакцию:	29 окт. 2017 г.
Принята к публикации:	6 февр. 2018 г.
Опубликована online:	14 февр. 2018 г.
Опубликована в печати:	1 апр. 2018 г.

Web of science:	WOS:000428099300008
Scopus:	2-s2.0-85042256559
РИНЦ:	35516739
Chemical Abstracts:	2018:284794
OpenAlex:	W2794282584

Пока нет цитирований