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Study of Hemocompatibility and Endothelial Cell Interaction of Tecoflex-Based Electrospun Vascular Grafts Научная публикация

Журнал International Journal of Polymeric Materials and Polymeric Biomaterials ((invalid ISSN 0367-8369)
ISSN: 0091-4037 , E-ISSN: 1563-535X
Вых. Данные Год: 2019, Том: 68, Номер: 1-3, Страницы: 34-43 Страниц : 10 DOI: 10.1080/00914037.2018.1525721
Ключевые слова Electrospinning; vascular graft; polyurethane; gelatin; bivalirudin; HUVEC; hemocompatibility
Авторы Chernonosova Vera S. 1,2 , Gostev Alexander A. 1 , Chesalov Yuriy A. 3 , Karpenko Andrey A. 1 , Karaskov Alexander M. 1 , Laktionov Pavel P. 1,2
Организации
1 Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia
2 Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia
3 Boreskov Institute of Catalysis, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia

Информация о финансировании (1)

1 Российский научный фонд 17-75-30009

Реферат: Ensuring long-term functioning and efficient endothelialization of small diameter vascular grafts (VG) is an urgent task of tissue engineering. A solution may be to use electrospun VGs prepared from blends polyurethane with gelatin and/or bivalirudin. Here, properties of 3D matrices were explored by SEM, contact angle measurements and IR spectroscopy, and their interaction with blood and endothelial cells was studied. Introduction of gelatin into matrices enhanced adhesion and proliferation of endotheliocytes and enabled adhesion of platelets, whereas bivalirudin inhibited platelet adhesion while having no negative effect on the adhesion and proliferation of endothelial cells.
Библиографическая ссылка: Chernonosova V.S. , Gostev A.A. , Chesalov Y.A. , Karpenko A.A. , Karaskov A.M. , Laktionov P.P.
Study of Hemocompatibility and Endothelial Cell Interaction of Tecoflex-Based Electrospun Vascular Grafts
International Journal of Polymeric Materials and Polymeric Biomaterials ((invalid ISSN 0367-8369). 2019. V.68. N1-3. P.34-43. DOI: 10.1080/00914037.2018.1525721 WOS Scopus РИНЦ CAPlus OpenAlex
Даты:
Поступила в редакцию: 13 июн. 2018 г.
Принята к публикации: 25 авг. 2018 г.
Опубликована online: 21 дек. 2018 г.
Опубликована в печати: 11 февр. 2019 г.
Идентификаторы БД:
Web of science: WOS:000467974500005
Scopus: 2-s2.0-85059010446
РИНЦ: 37413483
Chemical Abstracts: 2018:2604153
OpenAlex: W2905776205
Цитирование в БД:
БД Цитирований
Scopus 15
РИНЦ 13
Web of science 15
OpenAlex 19
Альметрики: