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Crystal Structure of 4-Benzylcarbamoyl-1-methylpyridin-1-ium Iodide: An Efficient Multimodal Antiviral Drug Full article

Journal Acta Crystallographica Section E
, E-ISSN: 2056-9890
Output data Year: 2017, Volume: 73, Number: 7, Pages: 967-970 Pages count : 4 DOI: 10.1107/s2056989017008155
Tags crystal structure; drug; polymorphism
Authors Drebushchak T.N. 1,2 , Kryukov Yu.A. 3 , Rogova A.I. 3 , Boldyreva E.V. 1,2
Affiliations
1 Institute of Solid State Chemistry and Mechanochemistry, SB RAS, ul. Kutateladze 18, Novosibirsk 630128, Russian Federation
2 Novosibirsk State University, ul. Pirogova 2, Novosibirsk 630090, Russian Federation
3 Institute for the Problems of the Technology of Energetic Materials, SB RAS, ul. Socialisticheskaia 1, Biisk 659322, Russian Federation.

Abstract: In the title compound, [MeC5H4NCONHCH2C6H5]I or C14H15N2O+I, a cation and an anion form an ionic pair linked by a strong N—HI hydrogen bond. In the crystal, ionic pairs linked by weak C—HI hydrogen bonds form infinite ribbons along the crystallographic a axis. Polymorphism screening varying crystallization solvents (water, acetone 90%–water, ethanol 90%–water, 2-propanol 90%–water, DMF, DMSO, methanol, acetonitrile) and conditions (solution temperature, heating and cooling protocols) did not reveal any other polymorphs than the one reported in this work.
Cite: Drebushchak T.N. , Kryukov Y.A. , Rogova A.I. , Boldyreva E.V.
Crystal Structure of 4-Benzylcarbamoyl-1-methylpyridin-1-ium Iodide: An Efficient Multimodal Antiviral Drug
Acta Crystallographica Section E. 2017. V.73. N7. P.967-970. DOI: 10.1107/s2056989017008155 WOS Scopus РИНЦ AN OpenAlex
Files: Full text from publisher
Dates:
Submitted: May 17, 2017
Accepted: Jun 1, 2017
Published online: Jun 7, 2017
Published print: Jul 1, 2017
Identifiers:
Web of science: WOS:000404860900010
Scopus: 2-s2.0-85023197405
Elibrary: 31055329
Chemical Abstracts: 2017:1134161
OpenAlex: W2623250566
Citing:
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Web of science 3
Scopus 3
OpenAlex 3
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