Synthesis of Pharmaceutically Relevant Terpene Amines via One-Pot Alcohol Amination over Gold Catalysts | Sciact - CRIS-system of Boreskov Institute of Catalysis

Synthesis of Pharmaceutically Relevant Terpene Amines via One-Pot Alcohol Amination over Gold Catalysts Conference Abstracts

Conference

The 8th Tokyo Conference on Advanced Catalytic Science and Technology
05-10 Aug 2018 , Токио

Source

The 8th Tokyo Conference on Advanced Catalytic Science and Technology
Compilation, 2018.

Output data

Year: 2018, Article number : P3013, Pages count : 2

Tags

amination, gold catalyst, biomass

Authors

Demidova Yuliya S. ^1,2 , Simakova Irina L. ^1,2 , Suslov Evgeny V. ³ , . Mozhajcev Evgeny S ³ , Konstantin P.Volcho ^2,3 , Salakhutdinov Nariman F. ^2,3 , Simakov Andrey V. ⁴ , Murzin Dmitry Yu. ⁵

Affiliations

1	Boreskov Institute of Catalysis, Novosibirsk, 630090, Russia
2	Novosibirsk State University, Novosibirsk, 630090, Russia
3	Novosibirsk Institute of Organic Chemistry, Novosibirsk, 630090, Russia
4	Universidad Nacional Autónoma de México, Centro de Nanociencias y Nanotecnología, Ensenada, 22860, México
5	Process Chemistry Centre, Åbo Akademi University, Turku/Åbo, FI-20500, Finland

Funding (1)

Russian Foundation for Basic Research

16-33-60028

One-pot terpene alcohols amination was studied over nanosized gold catalysts supported on metal oxides with equimolar amounts of the substrates under nitrogen pressure. The products distribution and conversion were found to depend on support nature, catalyst redox activation and active metal component composition. The reaction kinetics was modeled based on the mechanistic considerations with the catalyst deactivation step introduced into the mechanism. The effect of the substrate structure was explored. Introduction of hydrogen donors was efficient for controlled hydrogenation of C=N bond preserving C=C bond without addition of external molecular hydrogen resulting in the enhanced yield of the desired amine

Demidova Y.S. , Simakova I.L. , Suslov E.V. , . Mozhajcev E.S. , K.P.V. , Salakhutdinov N.F. , Simakov A.V. , Murzin D.Y.
Synthesis of Pharmaceutically Relevant Terpene Amines via One-Pot Alcohol Amination over Gold Catalysts
In compilation The 8th Tokyo Conference on Advanced Catalytic Science and Technology. 2018.

No identifiers

Пока нет цитирований