Chiral Autoamplification Meets Dynamic Chirality Control to Suggest Non-Autocatalytic Chemical Model of Prebiotic Chirality Amplification Научная публикация
| Журнал |
Research
ISSN: 2096-5168 , E-ISSN: 2639-5274 |
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| Вых. Данные | Год: 2019, Том: 2019, Номер статьи : 4756025, Страниц : 9 DOI: 10.34133/2019/4756025 | ||||||
| Ключевые слова | Additives; Catalysts; Chirality; Manganese compounds | ||||||
| Авторы |
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| Организации |
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Информация о финансировании (3)
| 1 | Федеральное агентство научных организаций России | 0303-2016-0005 |
| 2 | Федеральное агентство научных организаций России | 0303-2016-0001 |
| 3 | Российский фонд фундаментальных исследований | 18-33-20078 |
Реферат:
Oxidative kinetic resolution of 1-phenylethanol in the presence of manganese complexes, bearing conformationally non-rigid achiral bis-amine-bis-pyridine ligands, in the absence of any exogenous chiral additives, is reported. The only driving force for the chiral discrimination is the small initial enantiomeric imbalance of the scalemic (non-racemic) substrate: the latter dynamically controls the chirality of the catalyst, serving itself as the chiral auxiliary. In effect, the ee of 1-phenylethanol increases monotonously over the reaction course. This dynamic control of catalyst chirality by the substrate has been unprecedented; a consistent kinetic model for this process is presented. The reported
catalyzed substrate self-enantioenrichment mechanism is discussed in relation to the problem of prebiotic chirality amplification.
Библиографическая ссылка:
Talsi E.P.
, Bryliakova A.A.
, Ottenbacher R.V.
, Rybalova T.V.
, Bryliakov K.P.
Chiral Autoamplification Meets Dynamic Chirality Control to Suggest Non-Autocatalytic Chemical Model of Prebiotic Chirality Amplification
Research. 2019.
V.2019. 4756025
:1-9. DOI: 10.34133/2019/4756025
WOS
Scopus
РИНЦ
CAPlus
PMID
OpenAlex
Chiral Autoamplification Meets Dynamic Chirality Control to Suggest Non-Autocatalytic Chemical Model of Prebiotic Chirality Amplification
Research. 2019.
V.2019. 4756025
:1-9. DOI: 10.34133/2019/4756025
WOS
Scopus
РИНЦ
CAPlus
PMID
OpenAlex
Файлы:
Полный текст от издателя
Даты:
| Поступила в редакцию: | 30 июл. 2019 г. |
| Принята к публикации: | 16 сент. 2019 г. |
| Опубликована в печати: | 4 нояб. 2019 г. |
| Опубликована online: | 4 нояб. 2019 г. |
Идентификаторы БД:
| Web of science: | WOS:000524980100048 |
| Scopus: | 2-s2.0-85078782358 |
| РИНЦ: | 43244809 |
| Chemical Abstracts: | 2020:2203154 |
| PMID (PubMed): | 31922134 |
| OpenAlex: | W2988205493 |