Spontaneous Resolution and Super-coiling in Xerogels of the Products of Photo-Induced Formose Reaction | Sciact - CRIS-system of Boreskov Institute of Catalysis

Spontaneous Resolution and Super-coiling in Xerogels of the Products of Photo-Induced Formose Reaction Full article

Journal

Origins of Life and Evolution of Biospheres
ISSN: 0169-6149 , E-ISSN: 1573-0875

Output data

Year: 2019, Volume: 49, Number: 3, Pages: 187–196 Pages count : 10 DOI: 10.1007/s11084-019-09583-8

Tags

Formose reaction; Self-assembly; Supercoiling

Authors

Stovbun Sergey V. ¹ , Zanin Anatoly M. ¹ , Shashkov Mikhail V. ^2,3 , Skoblin Aleksey A. ¹ , Zlenko Dmitry V. ^1,4 , Tverdislov Vsevolod A. ⁵ , Mikhaleva Marya G. ¹ , Taran Oxana P. ^2,3 , Parmon Valentin N. ^2,3,6

Affiliations

1	N.N. Semenov Institute of Chemical Physics, RAS, Kosygina 4, Moscow, 119991, Russian Federation
2	G.K. Boreskov Institute of Catalysis SB RAS, Lavrentiev Avenue 5, Novosibirsk, 630090, Russian Federation
3	Novosibirsk State University, Pirogova 1, Novosibirsk, 630090, Russian Federation
4	Faculty of Biology, M.V. Lomonosov Moscow State University, Lenin Hills 1/12, Moscow, 119192, Russian Federation
5	Faculty of Physics, M.V. Lomonosov Moscow State University, Lenin Hills 1/2, Moscow, 119234, Russian Federation
6	Tomsk State University, Lenin Avenue 36, Tomsk, 634050, Russian Federation

Funding (1)

Federal Agency for Scientific Organizations

0082-2014-0011 (АААА-А17-117111600093-8)

This work addresses the supramolecular self-organization in the xerogels of formose reaction products. The UV-induced formose reaction was held in over-saturated formaldehyde solutions at 70∘C without a catalyst. The solutions of the obtained carbohydrates were dried on a glass slide, and the obtained xerogels demonstrated a prominent optical activity, while the initial solutions were optically inactive. The xerogels contained highly elongated crystalline elements of a helical structure as well as the isometric ones. Thus xerogel formation was accompanied by a spontaneous resolution of enantiomers and separation of different-shaped supramolecular structures. The thick helices were twisted of thinner ones, while the latter were twisted of elementary structures having a diameter much smaller than 400 nm. Similar structural hierarchy is typical of biological macromolecules (DNA, proteins, and cellulose). Summarizing the obtained results, we proposed a hypothetical mechanism explaining the amplification of the initial enantiomeric excess, as well as chiral and chemical purification of the substances which were essential for the evolution of Life to start. © 2019, Springer Nature B.V.

Stovbun S.V. , Zanin A.M. , Shashkov M.V. , Skoblin A.A. , Zlenko D.V. , Tverdislov V.A. , Mikhaleva M.G. , Taran O.P. , Parmon V.N.
Spontaneous Resolution and Super-coiling in Xerogels of the Products of Photo-Induced Formose Reaction
Origins of Life and Evolution of Biospheres. 2019. V.49. N3. P.187–196. DOI: 10.1007/s11084-019-09583-8 WOS Scopus РИНЦ PMID OpenAlex

Submitted:	Feb 20, 2019
Accepted:	Jul 17, 2019
Published print:	Sep 1, 2019
Published online:	Oct 22, 2019

Web of science:	WOS:000494193800001
Scopus:	2-s2.0-85074050379
Elibrary:	41816235
PMID:	31642022
OpenAlex:	W2981920334

DB	Citing
Scopus	10
Web of science	10
Elibrary	5
OpenAlex	11