Air Detoxification with Nanosize TiO2 Aerosol Tested on Mice | Sciact - CRIS-система Института катализа

Air Detoxification with Nanosize TiO2 Aerosol Tested on Mice Научная публикация

Журнал

Journal of Hazardous Materials
ISSN: 0304-3894 , E-ISSN: 1873-3336

Вых. Данные

Год: 2010, Том: 173, Номер: 1-3, Страницы: 40-46 Страниц : 7 DOI: 10.1016/j.jhazmat.2009.08.042

Ключевые слова

Anti-terrorism, Chemiluminescence, CWA, FTIR spectroscopy

Авторы

Besov A.S. ^1,2 , Krivova N.A. ³ , Vorontsov A.V. ^1,2 , Zaeva O.B. ³ , Kozlov D.V. ^1,2 , Vorozhtsov A.B. ^3,4 , Parmon V.N. ^1,2 , Sakovich G.V. ⁴ , Komarov V.F. ⁴ , Smirniotis P.G. ⁵ , Eisenreich N. ⁶

Организации

1	Boreskov Institute of Catalysis
2	Novosibirsk State University
3	Tomsk State University
4	Institute for Problems of Chemical and Energetic Technologies
5	Chemical and Materials Engineering Department, University of Cincinnati, Cincinnati
6	f Fraunhofer-Institut für Chemische Technologie ICT

Информация о финансировании (5)

1	Президиум РАН	27.56
2	North Atlantic Treaty Organization	SfP-981461
3	Международный научно-технический центр	3305
4	Сибирское отделение Российской академии наук	70
5	Сибирское отделение Российской академии наук	36

A method for fast air purification using high concentration aerosol of TiO(2) nanoparticles is evaluated in a model chemical catastrophe involving toxic vapors of diisopropyl fluorophosphate (DFP). Mice are used as human model in a closed 100 dm(3) chamber. Exposure of mice to 37 ppm of DFP vapor for 15 min resulted in acute poisoning. Spraying TiO(2) aerosol in 2 min after the start of exposure to DFP vapors resulted in quick removal of DFP vapors from the chamber's air. Animals did not show signs of poisoning after the decontamination experiment and exposure to TiO(2) aerosol alone. Reactive oxygen species (ROS) and antioxidant activity (AOA) of mice blood plasma were measured for animals exposed to sound of aerosol generator, DFP vapors, TiO(2) aerosol and DFP vapors+TiO(2) aerosol. Reduced ROS and increased AOA were found for mice exposure to sound, DFP and TiO(2) aerosol. Exposure to DFP and decontamination with TiO(2) nanoparticles resulted in decreased AOA in 48 h following the exposure. The results suggest that application of TiO(2) aerosol is a powerful method of air purification from toxic hydrolysable compounds with moderate health aftermaths and requires further study and optimization.

Besov A.S. , Krivova N.A. , Vorontsov A.V. , Zaeva O.B. , Kozlov D.V. , Vorozhtsov A.B. , Parmon V.N. , Sakovich G.V. , Komarov V.F. , Smirniotis P.G. , Eisenreich N.
Air Detoxification with Nanosize TiO2 Aerosol Tested on Mice
Journal of Hazardous Materials. 2010. V.173. N1-3. P.40-46. DOI: 10.1016/j.jhazmat.2009.08.042 WOS Scopus РИНЦ OpenAlex CAPlusCA PMID

Поступила в редакцию:	16 июн. 2009 г.
Принята к публикации:	10 авг. 2009 г.
Опубликована online:	18 авг. 2009 г.
Опубликована в печати:	15 янв. 2010 г.

≡ Web of science:	WOS:000273135600004
≡ Scopus:	2-s2.0-71749107902
≡ РИНЦ:	15335329
≡ OpenAlex:	W2010966893
≡ Chemical Abstracts:	2009:1481563
≡ Chemical Abstracts (print):	153:341842
≡ PMID (PubMed):	19765900

≡ Web of science	17	Сбор данных от 20.02.2026
≡ Scopus	19	Сбор данных от 22.02.2026
≡ РИНЦ	24	Сбор данных от 22.02.2026
≡ OpenAlex	21	Сбор данных от 22.02.2026