A Monolithic Column with a Sorbent Based on 1-Vinyl-1,2,4-Triazole for Hydrophilic HPLC Full article
| Journal |
Protection of Metals and Physical Chemistry of Surfaces
ISSN: 2070-2051 , E-ISSN: 2070-206X |
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| Output data | Year: 2020, Volume: 56, Number: 1, Pages: 49-53 Pages count : 5 DOI: 10.1134/s2070205119060248 | ||||
| Tags | HPLC, monolithic columns, porous polymers, 1-vinyl-1,2,4-triazole, hydrophilic interaction chromatography | ||||
| Authors |
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| Affiliations |
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Funding (1)
| 1 | Russian Foundation for Basic Research | 19-33-90006 (АААА-А19-119100390008-0) |
Abstract:
A monolithic chromatographic column for HPLC with a sorbent based on 1-vinyl-1,2,4-triazole has been prepared for the first time. It has been shown that, depending on the composition of the mobile phase (acetonitrile/water ratio), this column is able to operate in the modes of both reverse phase chromatography and hydrophilic chromatography. The dependences of the retention factor on the volume fraction of acetonitrile in the mobile phase have been studied for substances of acidic and basic nature. An example of the separation of the components of the pharmaceutical product Askofen-P on the prepared column has been provided.
Cite:
Patrushev Y.V.
, Sotnikova Y.S.
, Sidel’nikov V.N.
A Monolithic Column with a Sorbent Based on 1-Vinyl-1,2,4-Triazole for Hydrophilic HPLC
Protection of Metals and Physical Chemistry of Surfaces. 2020. V.56. N1. P.49-53. DOI: 10.1134/s2070205119060248 WOS Scopus РИНЦ AN OpenAlex
A Monolithic Column with a Sorbent Based on 1-Vinyl-1,2,4-Triazole for Hydrophilic HPLC
Protection of Metals and Physical Chemistry of Surfaces. 2020. V.56. N1. P.49-53. DOI: 10.1134/s2070205119060248 WOS Scopus РИНЦ AN OpenAlex
Original:
Патрушев Ю.В.
, Сотникова Ю.С.
, Сидельников В.Н.
Монолитная колонка с сорбентом на основе 1-винил-1,2,4-триазола для гидрофильной ВЭЖХ
Физикохимия поверхности и защита материалов. 2020. Т.56. №1. С.53-57. DOI: 10.31857/S004418561906024X РИНЦ OpenAlex
Монолитная колонка с сорбентом на основе 1-винил-1,2,4-триазола для гидрофильной ВЭЖХ
Физикохимия поверхности и защита материалов. 2020. Т.56. №1. С.53-57. DOI: 10.31857/S004418561906024X РИНЦ OpenAlex
Dates:
| Submitted: | Feb 28, 2019 |
| Accepted: | May 22, 2019 |
| Published print: | Jan 1, 2020 |
| Published online: | Apr 6, 2020 |
Identifiers:
| Web of science: | WOS:000524238900008 |
| Scopus: | 2-s2.0-85083177067 |
| Elibrary: | 43260636 |
| Chemical Abstracts: | 2020:648152 |
| OpenAlex: | W3015705611 |