Two-Step One-Pot Reductive Amination of Furanic Aldehydes Using CuAlOx Catalyst in a Flow Reactor Научная публикация
| Журнал |
Molecules
ISSN: 1420-3049 |
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| Вых. Данные | Год: 2020, Том: 25, Номер: 20, Номер статьи : 4771, Страниц : 7 DOI: 10.3390/molecules25204771 | ||
| Ключевые слова | reductive amination; 5-hydroxymethylfurfural; 5-acetoxymethylfurfural; Cu-based catalyst; Cu-Al mixed oxide; primary amines; imine hydrogenation; flow reactor | ||
| Авторы |
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| Организации |
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Информация о финансировании (1)
| 1 |
Российский научный фонд FWF Austrian Science Fund |
20-43-05002 |
Реферат:
Aminomethylhydroxymethylfuran derivatives are well known compounds which are used in the pharmaceutical industry. Reductive amination of 5-hydroxymethylfurfural (HMF) derived from available non-edible lignocellulosic biomass is an attractive method for the synthesis of this class of compounds. In the present study, the synthesis of N-substituted 5-(hydroxymethyl)-2-furfuryl amines and
5-(acetoxymethyl)-2-furfuryl amines was performed by two-step process, which includes the condensation of furanic aldehydes (HMF and 5-acetoxymethylfurfural) with primary amines in methanol on the first step and the reduction of obtained imines with hydrogen in a flow reactor over CuAlOx catalyst derived from layered double hydroxide on the second step. This process does not require isolation and purification of intermediate imines and can be used to synthesize a number of aminomethylhydroxymethylfurans in good to excellent yield.
Библиографическая ссылка:
Nuzhdin A.L.
, Bukhtiyarova M.V.
, Bukhtiyarov V.I.
Two-Step One-Pot Reductive Amination of Furanic Aldehydes Using CuAlOx Catalyst in a Flow Reactor
Molecules. 2020.
V.25. N20. 4771
:1-7. DOI: 10.3390/molecules25204771
WOS
Scopus
РИНЦ
CAPlusCA
PMID
OpenAlex
Two-Step One-Pot Reductive Amination of Furanic Aldehydes Using CuAlOx Catalyst in a Flow Reactor
Molecules. 2020.
V.25. N20. 4771
:1-7. DOI: 10.3390/molecules25204771
WOS
Scopus
РИНЦ
CAPlusCA
PMID
OpenAlex
Файлы:
Полный текст от издателя
Даты:
| Поступила в редакцию: | 26 сент. 2020 г. |
| Опубликована в печати: | 1 окт. 2020 г. |
| Принята к публикации: | 15 окт. 2020 г. |
| Опубликована online: | 17 окт. 2020 г. |
Идентификаторы БД:
| Web of science: | WOS:000585575100001 |
| Scopus: | 2-s2.0-85093652296 |
| РИНЦ: | 45205218 |
| Chemical Abstracts: | 2020:2221445 |
| Chemical Abstracts (print): | 174:7750 |
| PMID (PubMed): | 33080807 |
| OpenAlex: | W3093254304 |