Kinetic Aspects of Virus Targeting by Nanoparticles in vivo Научная публикация
| Журнал |
Journal of Biological Physics
ISSN: 0092-0606 , E-ISSN: 1573-0689 |
||||
|---|---|---|---|---|---|
| Вых. Данные | Год: 2021, Том: 47, Номер: 2, Страницы: 95-101 Страниц : 7 DOI: 10.1007/s10867-021-09570-z | ||||
| Ключевые слова | Nanoparticles; Viral infection; Inhibition; Association; Kinetic model | ||||
| Авторы |
|
||||
| Организации |
|
Информация о финансировании (2)
| 1 | Министерство науки и высшего образования Российской Федерации (с 15 мая 2018) | 0239-2021-0009 |
| 2 | Chalmers University of Technology |
Реферат:
One of the suggested ways of the use of nanoparticles in virology implies their association with and subsequent deactivation of virions. The conditions determining the efficiency of this approach in vivo are now not clear. Herein, I propose the first kinetic model describing the corresponding processes and clarifying these conditions. My analysis indicates that nanoparticles can decrease concentration of infected cells by a factor of one order of magnitude, but this decrease itself (without feedback of the immune system) is insufficient for full eradication of infection. It can, however, induce delay in the progress of infection, and this delay can help to form sufficient feedback of the immune system.
Библиографическая ссылка:
Zhdanov V.P.
Kinetic Aspects of Virus Targeting by Nanoparticles in vivo
Journal of Biological Physics. 2021.
V.47. N2. P.95-101. DOI: 10.1007/s10867-021-09570-z
WOS
Scopus
РИНЦ
PMID
OpenAlex
Kinetic Aspects of Virus Targeting by Nanoparticles in vivo
Journal of Biological Physics. 2021.
V.47. N2. P.95-101. DOI: 10.1007/s10867-021-09570-z
WOS
Scopus
РИНЦ
PMID
OpenAlex
Файлы:
Полный текст от издателя
Даты:
| Поступила в редакцию: | 29 мар. 2021 г. |
| Принята к публикации: | 26 апр. 2021 г. |
| Опубликована в печати: | 2 июн. 2021 г. |
| Опубликована online: | 2 июн. 2021 г. |
Идентификаторы БД:
| Web of science: | WOS:000657183300001 |
| Scopus: | 2-s2.0-85107414730 |
| РИНЦ: | 46817070 |
| PMID (PubMed): | 34080098 |
| OpenAlex: | W3165390432 |