Possibilities of Mechanochemical Synthesis of Apatites with Different Ca/P Ratios | Sciact - CRIS-system of Boreskov Institute of Catalysis

Possibilities of Mechanochemical Synthesis of Apatites with Different Ca/P Ratios Full article

Journal

Ceramics
, E-ISSN: 2571-6131

Output data

Year: 2022, Volume: 5, Number: 3, Pages: 404-422 Pages count : 19 DOI: 10.3390/ceramics5030031

Tags

bioceramics; calcium phosphates; hydroxyapatite; calcium-deficient apatite; calcium-rich apatite; tricalcium phosphate; synthesis; mechanochemistry

Authors

Chaikina Marina V. ¹ , Bulina Natalia V. ¹ , Vinokurova Olga B. ¹ , Gerasimov Konstantin B. ¹ , Prosanov Igor Yu. ¹ , Kompankov Nikolay B. ² , Lapina Olga B. ³ , Papulovskiy Evgeniy S. ³ , Ishchenko Arcady V. ³ , Makarova Svetlana V. ¹

Affiliations

1	Institute of Solid State Chemistry and Mechanochemistry, Siberian Branch of the Russian Academy of Sciences, Kutateladze Str. 18, 630128 Novosibirsk, Russia
2	A.V. Nikolaev Institute of Inorganic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentyev Ave. 3, 630090 Novosibirsk, Russia
3	G.K. Boreskov Institute of Catalysis, Siberian Branch of Russian Academy of Sciences, Pr. Akad. Lavrentieva 5, 630090 Novosibirsk, Russia

Funding (1)

Ministry of Science and Higher Education of the Russian Federation

075-00521-21-00 (121032500064-8) (FWUS-2021-0009)

Apatite is widely used in medicine as a biomaterial for bone tissue restoration. Properties of apatite depend on its composition, including the Ca/P ratio. This paper shows what range of Ca/P ratio can be attained in apatite by the mechanochemical method of synthesis, providing fast formation of a single-phase product. The synthesis was carried out from a reaction mixture of CaHPO4 and CaO at different Ca/P ratios in the range of 1.17–2.10. The products were studied by PXRD, FTIR and NMR spectroscopy, HRTEM, and STA. In mixtures with a low initial Ca/P ratio (1.17–1.48), directly in the mill, the formation of calcium orthophosphate with whitlockite structure containing an HPO₄²⁻ group and structural water is shown for the first time. This phosphate has structure similar to that of whitlockites of hydrothermal origin and differs from high-temperature β-tricalcium phosphate that has composition Ca₃(PO₄ )₃. A series of samples of apatite was obtained with varied composition, which depends on the initial Ca/P ratio. At Ca/P < 1.67, the formation of two types of calcium-deficient apatite was documented. At Ca/P > 1.67, the existence of two types of calcium-rich apatite is confirmed.

Chaikina M.V. , Bulina N.V. , Vinokurova O.B. , Gerasimov K.B. , Prosanov I.Y. , Kompankov N.B. , Lapina O.B. , Papulovskiy E.S. , Ishchenko A.V. , Makarova S.V.
Possibilities of Mechanochemical Synthesis of Apatites with Different Ca/P Ratios
Ceramics. 2022. V.5. N3. P.404-422. DOI: 10.3390/ceramics5030031 WOS Scopus РИНЦ AN OpenAlex

Submitted:	Jul 15, 2022
Accepted:	Jul 30, 2022
Published online:	Aug 3, 2022
Published print:	Sep 1, 2022

Web of science:	WOS:000857688400001
Scopus:	2-s2.0-85138746308
Elibrary:	52253202
Chemical Abstracts:	2022:2500150
OpenAlex:	W4289704810

DB	Citing
Scopus	23
Web of science	21
Elibrary	18
OpenAlex	27