Effect of Carbonmineral Sorbent with Nanofiber on the Parameters of Erythrocytes of Erythrocyte Concentrates IN VITRO | Sciact - CRIS-система Института катализа

Effect of Carbonmineral Sorbent with Nanofiber on the Parameters of Erythrocytes of Erythrocyte Concentrates IN VITRO Тезисы доклада

Конференция

Computational Technologies in Cognitive Science, Genomics and Biomedicine : 2022 IEEE Ural-Siberian Conference
07-08 июл. 2022 , Novosibirsk

Сборник

Proceedings - 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine (CSGB), July 7-8, 2022, Novosibirsk, Russia
Сборник, 2022. 392 c. ISBN 978-1-6654-5288-5.

Вых. Данные

Год: 2022, Страницы: 300-303 Страниц : 4 DOI: 10.1109/csgb56354.2022.9865399

Ключевые слова

sorbents, aluminum oxide, polydimethylsiloxane, carbon nanofiber, erythrocytes, scanning flow cytometry, safety

Авторы

Smagin Alexander ¹ , Rachkovskaya Lubov ¹ , Nimaev Vadim ¹ , Yastrebova Ekaterina ² , Rachkovsky Edmund ¹ , Volodin Alexander ³ , Maltsev Valery ² , Letyagin Andrey ¹

Организации

1	Siberian Branch of the Russian, Academy of Sciences, RICEL - Branch of IC&G, SB RAS, Novosibirsk, Russia
2	Siberian Branch of the Russian, Academy of Sciences, V.V. Voevodsky Institute of Chemical, Kinetics and Combustion, SB RAS, Novosibirsk, Russia
3	Boreskov Institute of Catalysis SB RAS, Novosibirsk, Russia

Информация о финансировании (1)

Министерство науки и высшего образования Российской Федерации (с 15 мая 2018)

075-00707-2200 (122022800132-1) (FWNR-2022-0009)

As preventive, curative and restorative measures in modern conditions of the spread of infectious diseases (Covid 19), the use of sorption materials and detoxification methods with their use in hemosorption are of particular importance. It is known that hemosorption is an effective method of detoxification of the body, and no less important is the use of safe sorbents in relation to the shaped elements of blood, both time-tested sorbents and new, less studied, but more promising from the point of view of their safe production technology. The purpose of this work is to study with the help of scanning flow cytometry the effect of a sorbent with carbon nanofiber A1203@PDMS/CNF in comparison with a carbon-free sorbent A1203@PDMS on morphofunctional parameters erythrocytes. The study of the physico-chemical properties of sorbents was carried out according to standard methods. The biological properties of sorbents were evaluated by its effect on erythrocytes of erythrocyte concentrate during hemoperfusion of blood through columns with sorbents using the method of scanning flow cytometry according to the standard method. The data obtained using the method of scanning flow cytometry made it possible to conclude that the studied sorbents do not have a traumatic effect on the morphofunctional parameters of erythrocytes. The introduction of carbon nanofiber into the composition of the sorbent in an amount of 0.02% improves the functional parameters of blood erythrocytes both in comparison with the initial donor blood and compared to the sorbent without carbon.

Smagin A. , Rachkovskaya L. , Nimaev V. , Yastrebova E. , Rachkovsky E. , Volodin A. , Maltsev V. , Letyagin A.
Effect of Carbonmineral Sorbent with Nanofiber on the Parameters of Erythrocytes of Erythrocyte Concentrates IN VITRO
В сборнике Proceedings - 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine (CSGB), July 7-8, 2022, Novosibirsk, Russia. 2022. – C.300-303. – ISBN 978-1-6654-5288-5. DOI: 10.1109/csgb56354.2022.9865399 Scopus РИНЦ OpenAlex

Scopus:	2-s2.0-85138470808
РИНЦ:	49955809
OpenAlex:	W4293812407

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