Kinetic Aspects of the Interplay of Cancer and the Immune System Научная публикация
| Журнал |
Biophysical Reviews and Letters
ISSN: 1793-0480 , E-ISSN: 1793-7035 |
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| Вых. Данные | Год: 2019, Том: 14, Номер: 2, Страницы: 101-114 Страниц : 4 DOI: 10.1142/s1793048019400010 | ||||
| Ключевые слова | Cancer; immune system; initiation; lifetime risk; tumor growth | ||||
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Реферат:
The understanding of the interplay between cancer and the immune system is still limited. Herein, I focus on two aspects of this interplay. First, I propose a kinetic model describing the likely role of the immune system in the lifetime risk of cancer at the level of the whole human population. For each tissue, the risk is predicted to be influenced by the heterogeneity of the population and to depend exponentially on time. The expression for the risk does not, however, depend explicitly on the total number of divisions of the corresponding stem cells. For this reason, the correlation with the latter number can only be indirect. Second, using another kinetic framework, I describe how the growth of a few tumors can depend on their interaction via the immune system. The analysis shows that depending on specific details, the tumors of different sizes tend either to reach the same size or remain to be of different sizes.
Библиографическая ссылка:
Zhdanov V.P.
Kinetic Aspects of the Interplay of Cancer and the Immune System
Biophysical Reviews and Letters. 2019. V.14. N2. P.101-114. DOI: 10.1142/s1793048019400010 РИНЦ OpenAlex
Kinetic Aspects of the Interplay of Cancer and the Immune System
Biophysical Reviews and Letters. 2019. V.14. N2. P.101-114. DOI: 10.1142/s1793048019400010 РИНЦ OpenAlex
Даты:
| Поступила в редакцию: | 7 мая 2019 г. |
| Принята к публикации: | 26 июл. 2019 г. |
| Опубликована в печати: | 16 сент. 2019 г. |
Идентификаторы БД:
| РИНЦ: | 63426000 |
| OpenAlex: | W2976896705 |