XPS Study of Pharmacological Substances Mechanochemically Immobilized on the Surface of Alumina | Sciact - CRIS-system of Boreskov Institute of Catalysis

XPS Study of Pharmacological Substances Mechanochemically Immobilized on the Surface of Alumina Full article

Journal

Journal of Structural Chemistry
ISSN: 0022-4766 , E-ISSN: 1573-8779

Output data

Year: 2011, Volume: 52, Number: Supplement, Pages: S137-S144 Pages count : 8 DOI: 10.1134/S0022476611070183

Tags

mechanochemistry, nanocomposites, X-ray photoelectron spectroscopy, medicinal substances, piroxicam, meloxicam, alumina

Authors

Nizovskii A.I. ¹ , Kalinkin A.V. ¹ , Shakhtshnejder T.P. ^2,3 , Dyakonova M.A. ³ , Myz S.A. ^2,3 , Boldyreva E.V. ^2,3 , Kumar R. ⁴

Affiliations

1	G. K. Boreskov Institute of Catalysis, Siberian Division, Russian Academy of Sciences, Novosibirsk
2	Institute of Solid State Chemistry and Mechanochemistry, Siberian Division, Russian Academy of Sciences, Novosibirsk
3	Scientific-Educational Center “Molecular Design and Environmentally Safe Technologies” at the Novosibirsk State University, Novosibirsk
4	National Metallurgical Laboratory, Jamshedpur, India

Funding (2)

1	Civilian Research and Development Foundation	RUX0-008-NO-06
2	Russian Foundation for Basic Research	09-03-92658

Piroxicam and meloxicam nanocomposites with alumina were synthesized by mechanochemical treatment of medicinal substances mixed with the oxide. X-ray photoelectron spectroscopy demonstrated that interaction of the components during mechanical activation proceeds via binding the amide and sulfate groups in the molecules of medicinal substances with the active sites of alumina surface. XPS studies confirmed the formation of “core-shell” composites with the shell represented by medicinal substances distributed over the support surface.

Nizovskii A.I. , Kalinkin A.V. , Shakhtshnejder T.P. , Dyakonova M.A. , Myz S.A. , Boldyreva E.V. , Kumar R.
XPS Study of Pharmacological Substances Mechanochemically Immobilized on the Surface of Alumina
Journal of Structural Chemistry. 2011. V.52. NSupplement. P.S137-S144. DOI: 10.1134/S0022476611070183 РИНЦ ANCAN OpenAlex

Низовский А.И. , Калинкин А.В. , Шахтшнейдер Т.П. , Дьяконова М.А. , Мызь С.А. , Болдырева Е.В. , Кумар Р.
Исследование методом РФЭС механохимически иммобилизованных на поверхности оксида алюминия фармакологических субстанций
Журнал структурной химии. 2011. Т.52. №7. С.S141-S147. RSCI РИНЦ

Submitted:	Oct 26, 2010
Published print:	Dec 1, 2011
Published online:	Jan 28, 2012

Elibrary:	19136903
Chemical Abstracts:	2012:137140
Chemical Abstracts (print):	156:570392
OpenAlex:	W2076228945

DB	Citing
Elibrary	1
OpenAlex	1