The p-Toluenesulfonic Acid-Catalyzed Transformation of Polyfluorinated 2-Alkynylanilines to 2-Aminoarylketones and Indoles Full article
| Journal |
Tetrahedron Letters
ISSN: 0040-4039 |
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| Output data | Year: 2015, Volume: 56, Number: 39, Pages: 5328-5332 Pages count : 5 DOI: 10.1016/j.tetlet.2015.07.078 | ||||||
| Tags | p-TSA-catalyzed hydration, Polyfluorinated 2-alkynylanilines, Polyfluorinated 2-aminoarylketones, Polyfluorinated indoles | ||||||
| Authors |
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| Affiliations |
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Funding (1)
| 1 | Russian Foundation for Basic Research | 14-03-00108 |
Abstract:
The reactivity of a series of polyfluorinated 2-alkynylanilines with various alcohols using p-TSA has been studied. It was found that hydration of the triple bond gave rise to polyfluorinated 2-aminoarylketones and competed with an electrophilic heterocyclization reaction leading to polyfluorinated indoles. The dependence of the reaction pathways on the nature of the alkynylaniline substituents has been examined.
Cite:
Politanskaya L.
, Shteingarts V.
, Tretyakov E.
, Potapov A.
The p-Toluenesulfonic Acid-Catalyzed Transformation of Polyfluorinated 2-Alkynylanilines to 2-Aminoarylketones and Indoles
Tetrahedron Letters. 2015. V.56. N39. P.5328-5332. DOI: 10.1016/j.tetlet.2015.07.078 WOS Scopus РИНЦ ANCAN OpenAlex
The p-Toluenesulfonic Acid-Catalyzed Transformation of Polyfluorinated 2-Alkynylanilines to 2-Aminoarylketones and Indoles
Tetrahedron Letters. 2015. V.56. N39. P.5328-5332. DOI: 10.1016/j.tetlet.2015.07.078 WOS Scopus РИНЦ ANCAN OpenAlex
Dates:
| Submitted: | Jun 9, 2015 |
| Accepted: | Jul 29, 2015 |
| Published online: | Aug 3, 2015 |
| Published print: | Sep 1, 2015 |
Identifiers:
| Web of science: | WOS:000361252200004 |
| Scopus: | 2-s2.0-84939653656 |
| Elibrary: | 24469299 |
| Chemical Abstracts: | 2015:1273247 |
| Chemical Abstracts (print): | 163:473848 |
| OpenAlex: | W1070156391 |