Mn Catalyzed Bioinspired Oxidation of Aliphatic C-H Groups: Chemo-, Regio-, Stereoselectivity, and Mechanism - Conference attendances | Sciact - CRIS-system of Boreskov Institute of Catalysis

Mn Catalyzed Bioinspired Oxidation of Aliphatic C-H Groups: Chemo-, Regio-, Stereoselectivity, and Mechanism Conference attendances

Language

Английский

Participant type

Ключевой

Conference

XXII International Symposium on Homogeneous Catalysis
24-29 Jul 2022 , Lisbon

Authors

Ottenbacher Roman Viktorovich ¹ , Bryliakova Anna Aleksandrovna ^1,2 , Kurganskii Vladimir Ivanovich ¹ , Bryliakov Konstantin Petrovich ¹

Affiliations

1	Novosibirsk National Research University
2	Novosibirsk Scientific and Technical Center, Novosibirsk R&D Center

Herewith, our recent results in the chemo-, regio-, and stereoselective catalytic oxygenation of C(sp3)-H groups with hydrogen peroxide in the presence Mn complexes with bis-imino-bis-pyridylmethyl and related N4-donor ligands are summarized. Under optimal conditions, secondary and tertiary C-H groups can be hydroxylated in good to high yields, chemo-, and stereoselectivities (up to 97 % ee). The use of “polarity reversal” approach for the suppression of overoxidation of methylene groups to carbonyl groups is exemplified for enantioselective benzylic C-H hydroxylations.

Ottenbacher R.V. , Bryliakova A.A. , Kurganskii V.I. , Bryliakov K.P.
Mn Catalyzed Bioinspired Oxidation of Aliphatic C-H Groups: Chemo-, Regio-, Stereoselectivity, and Mechanism
XXII International Symposium on Homogeneous Catalysis 24-29 Jul 2022