One-Pot Terpene Alcohols Amination Towards Biologically Active Compounds Synthesis - Conference attendances | Sciact - CRIS-system of Boreskov Institute of Catalysis

One-Pot Terpene Alcohols Amination Towards Biologically Active Compounds Synthesis Conference attendances

Language

Английский

Participant type

Устный

Conference

EuropaCat-XIII: 13th European Congress on Catalysis
27-31 Aug 2017 , Florence

Authors

Demidova Yu.S. ^1,2 , Simakova I.L. ^1,2 , Suslov E.V. ³ , Beloshapkin S. ⁴ , Volcho K.P. ^2,3 , Salakhutdinov N.F. ^2,3 , Simakov A.V. ⁵ , Murzin D.Yu. ⁶

Affiliations

1	Boreskov Institute of Catalysis SB RAS
2	Novosibirsk National Research University
3	N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry
4	University of Limerick
5	National Autonomous University of Mexico
6	Åbo Akademi University

One-pot myrtenol amination was studied in the presence of nanosized gold catalysts supported on different metal oxides with equimolar amounts of the substrates in the temperature range 413-453 K under nitrogen pressure. The products distribution and conversion were found to depend strongly on support nature, catalyst redox activation and active metal component composition. The reaction kinetics was modeled based on the mechanistic considerations with the catalyst deactivation step introduced into the mechanism. The effect of the substrate structure was explored. Introduction of hydrogen donors was shown to be efficient for controlled hydrogenation of the C=N bond preserving the C=C bond without addition of external molecular hydrogen resulting in the enhanced yield of the desired amine.

Demidova Y.S. , Simakova I.L. , Suslov E.V. , Beloshapkin S. , Volcho K.P. , Salakhutdinov N.F. , Simakov A.V. , Murzin D.Y.
One-Pot Terpene Alcohols Amination Towards Biologically Active Compounds Synthesis
EuropaCat-XIII: 13th European Congress on Catalysis 27-31 Aug 2017