Abstract: This lecture is focused on dynamic nonlinear effects (DNLEs) [2], with the catalyst systems exhibiting variation of enantioselectivity over the reaction course; this variation is caused by the interactions of the catalyst with the chiral product or substrate, whose concentrations change as the reaction proceeds (Figure 1). Namely, such phenomena as asymmetric autoinduction [3], asymmetric autocatalysis [4], and asymmetric autoamplification [5] are considered, and examples of reactions exhibiting such effects, are presented. Whenever available, key details of the molecular mechanisms responsible for the observed nonlinearities are provided. Possible implications of dynamic nonlinear effects in asymmetric catalysis into the problem of prebiotic emergence of chirality on Earth are discussed.

Cite: Ottenbacher R.V. , Talsi E.P. , Bryliakov K.P.
Dynamic Nonlinear Effects in Asymmetric Catalysis
XI International Conference Mechanisms of Catalytic Reactions 07-11 Oct 2019