Simulation of the Growth of Neurospheres Full article
Journal |
Europhysics Letters
ISSN: 0295-5075 , E-ISSN: 1286-4854 |
||||
---|---|---|---|---|---|
Output data | Year: 2004, Volume: 68, Number: 1, Pages: 134-140 Pages count : 7 DOI: 10.1209/epl/i2004-10170-1 | ||||
Tags | PLURIPOTENT STEM-CELL; DIFFERENTIAL ADHESION; MORPHOGENESIS; ASTROCYTES; ENSEMBLE; NEURONS | ||||
Authors |
|
||||
Affiliations |
|
Funding (1)
1 | European Commission | 505868 FP6-2002-NMP-1 STREP NANOCUES |
Abstract:
Under appropriate conditions, the neural stem cells are able to proliferate and to form suspended neurospheres containing stem cells and neuronal and glial progenitors in different stages of differentiation. Our lattice Monte Carlo simulations, taking into account the effect of spatial constraints and cell-cell adhesion on cell diffusion and division, show that i) the neurosphere-size distribution is very broad and ii) the spatial distribution of various cells inside neurospheres is heterogeneous.
Cite:
Zhdanov V.P.
, Kasemo B.
Simulation of the Growth of Neurospheres
Europhysics Letters. 2004. V.68. N1. P.134-140. DOI: 10.1209/epl/i2004-10170-1 WOS Scopus РИНЦ
Simulation of the Growth of Neurospheres
Europhysics Letters. 2004. V.68. N1. P.134-140. DOI: 10.1209/epl/i2004-10170-1 WOS Scopus РИНЦ
Dates:
Submitted: | May 13, 2004 |
Accepted: | Jul 30, 2004 |
Published print: | Oct 1, 2004 |
Published online: | Jan 2, 2007 |
Identifiers:
Web of science | WOS:000224990000021 |
Scopus | 2-s2.0-5644253323 |
Elibrary | 13460188 |
Chemical Abstracts | 2004:959516 |
OpenAlex | W2095137413 |