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The Effect of Chemical Treatment Conditions of Titanium Dioxide Sols on Their Dispersion and Cytotoxic Properties Full article

Conference 3rd Internetional Conference on Industrial Biotechnology, IBIC2012
24-27 Jun 2012 , Palermo
Journal Chemical Engineering Transactions
ISSN: 1974-9791
Output data Year: 2012, Volume: 27, Pages: 241-246 Pages count : 6 DOI: 10.3303/CET1227041
Tags Chemical modification; Dispersions; Electrolytes; Ethers; Industrial poisons; Nanoparticles; Positive ions; Sols; Surface treatment; Titanium
Authors Ismagilov Zinfer R. 1 , Shikina Nadezhda V. 1 , Bessudnova Elena V. 1 , Korneev Denis V. 3 , Ishchenko Arkadyi V. 1 , Chesalov Yurii A. 1 , Vladimirova A.V. 2 , Ryabchikova Elena I. 2
Affiliations
1 Boreskov Institute of Catalysis, 5, Pr. Akad. Lavrentieva, 630090, Novosibirsk, Russia
2 Institute of Chemical Biology and Fundamental Medicine, 8, Pr. Akad. Lavrentieva, 630090, Novosibirsk, Russia
3 State Research Center of Virology & Biotechnology, Vector, bld. 12, Koltsovo, 630559, Novosibirsk oblast, Russia

Funding (3)

1 Russian Foundation for Basic Research 11-04-01408 (01201158854)
2 The Ministry of Education and Science of the Russian Federation 16.512.11.2267 (01201176480)
3 The Ministry of Education and Science of the Russian Federation 2.1.1/5642

Abstract: The effect of neutralization conditions of TiO 2 acid sol obtained by hydrolysis of titanium tetraisopropoxide (the nature of monovalent cation (Li +, Na +, NH 4 +) of electrolyte, chemical nature of a dialyzing solution, and surface modification of nanoparticles with glycidyl isopropyl ether (GE)) on TiO 2 dispersion and cytotoxic properties was investigated. The initial TiO 2 and sols after treatment were examined by a set of physicochemical methods: XRD, CS, SAXS, AFM, and TEM. The in vitro toxic effect of nanoparticles was studied on a monolayer of MDCK (Madin-Darby canine kidney) cells by trypan blue staining. It was shown that chemical nature of the electrolyte cation affects sol agglomeration, which increases in a series Li + > Na + > NH 4 +, and the use of phosphate buffer for sol dialysis facilitates the formation of more uniform disperse systems. Surface modification of TiO 2 nanoparticles (TiO 2-NPs) with glycidyl isopropyl ether (GE) was found to decrease its toxic effect on the cells.
Cite: Ismagilov Z.R. , Shikina N.V. , Bessudnova E.V. , Korneev D.V. , Ishchenko A.V. , Chesalov Y.A. , Vladimirova A.V. , Ryabchikova E.I.
The Effect of Chemical Treatment Conditions of Titanium Dioxide Sols on Their Dispersion and Cytotoxic Properties
Chemical Engineering Transactions. 2012. V.27. P.241-246. DOI: 10.3303/CET1227041 WOS Scopus РИНЦ OpenAlex
Identifiers:
Web of science: WOS:000319509400041
Scopus: 2-s2.0-84864417644
Elibrary: 20477627
OpenAlex: W2559391208
Citing:
DB Citing
Web of science 12
Scopus 13
Elibrary 17
OpenAlex 11
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