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Stochastic Model of the Formation of Cancer Metastases via Cancer Stem Cells Научная публикация

Журнал European Biophysics Journal with Biophysics Letters
ISSN: 0175-7571 , E-ISSN: 1432-1017
Вых. Данные Год: 2008, Том: 37, Номер: 8, Страницы: 1329-1334 Страниц : 6 DOI: 10.1007/s00249-008-0341-9
Ключевые слова Cancer, Cancer stem and progenitor cells, Mean-field kinetic equations, Metastases, Monte Carlo simulations, Premetastatic niches, Proliferation, differentiation and death of cells
Авторы Zhdanov Vladimir P. 1,2
Организации
1 Department of Applied Physics, Chalmers University of Technology, 412 96 Gothenburg, Sweden
2 Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk 630090, Russia

Информация о финансировании (1)

1 Chalmers University of Technology

Реферат: The author presents Monte Carlo simulations of the temporal kinetics of the formation of cancer metastases with emphasis on cancer stem cells. The model used implies the existence of premetastatic niches. The population of cancer stem cells located outside tumors and inducing the formation of new tumors in niches is considered to be heterogeneous. If the niches are equivalent with respect to the formation of metastases, the kinetics are predicted to exhibit an induction period and then rapid growth of the number of metastases. If the niches are heterogeneous, the kinetics are found to be more gradual.
Библиографическая ссылка: Zhdanov V.P.
Stochastic Model of the Formation of Cancer Metastases via Cancer Stem Cells
European Biophysics Journal with Biophysics Letters. 2008. V.37. N8. P.1329-1334. DOI: 10.1007/s00249-008-0341-9 WOS Scopus РИНЦ OpenAlex
Даты:
Поступила в редакцию: 8 дек. 2007 г.
Принята к публикации: 17 апр. 2008 г.
Опубликована online: 8 мая 2008 г.
Опубликована в печати: 1 окт. 2008 г.
Идентификаторы БД:
Web of science: WOS:000259247200006
Scopus: 2-s2.0-51849111910
РИНЦ: 13572183
OpenAlex: W2005190572
Цитирование в БД:
БД Цитирований
Web of science 12
Scopus 14
РИНЦ 14
OpenAlex 12
Альметрики: