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Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic? Научная публикация

Журнал

Письма в Журнал экспериментальной и теоретической физики
ISSN: 0370-274X

Вых. Данные

Год: 2011, Том: 93, Номер: 1, Страницы: 43-47 Страниц : 5

Ключевые слова

Monte Carlo JETP Letter Regulatory Site Monte Carlo Calculation Genetic Network

Авторы

Zhdanov V.P. ^1,2

Организации

1	Boreskov Institute of Catalysis RAS, 630090 Novosibirsk, Russia
2	Department of Applied Physics, Chalmers University of Technology, S-412 96 Göteborg, Sweden

Complex mRNA-protein networks with distributed regulation of gene transcription are often mimicked by random Boolean networks. According to this mapping, the gene-expression kinetics are expected to depend strongly on the network connectivity, mm. Specifically, the kinetics are predicted to be oscillatory or chaotic for m>2m>2. We analyze this problem in more detail by using an accurate model explicitly describing the mRNA-protein interplay with randomly organized transcriptional regulation. Contrary to the expectations, our mean-field calculations and Monte Carlo simulations performed for m=1m=1, 22 and 44 show that oscillations and chaos are lacking irrespective of m

Zhdanov V.P.
Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic?
Письма в Журнал экспериментальной и теоретической физики. 2011. V.93. N1. P.43-47. РИНЦ

Zhdanov V.P.
Are the Complex Distributed Genetic Networks Inherently Oscillatory and Chaotic?
Journal of Experimental and Theoretical Physics Letters (JETP Letters). 2011. V.93. N1. P.41-45. DOI: 10.1134/S0021364011010097 WOS Scopus РИНЦ CAPlusCA OpenAlex

Поступила в редакцию:

16 нояб. 2010 г.

РИНЦ:

16288895

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