High-Resolution 3D Proton MRI of Hyperpolarized Gas Enabled by Parahydrogen and Rh/TiO2 Heterogeneous Catalyst | Sciact - CRIS-system of Boreskov Institute of Catalysis

High-Resolution 3D Proton MRI of Hyperpolarized Gas Enabled by Parahydrogen and Rh/TiO2 Heterogeneous Catalyst Full article

Journal

Chemistry - A European Journal
ISSN: 0947-6539 , E-ISSN: 1521-3765

Output data

Year: 2014, Volume: 20, Number: 37, Pages: 11636-11639 Pages count : 4 DOI: 10.1002/chem.201403604, 10.1002/chem.201404052, 10.1002/chem.201490154

Tags

heterogeneous catalysis, hyperpolarized gas, magnetic resonance imaging, parahydrogen, supported catalysts

Authors

Kovtunov Kirill V. ^1,2 , Barskiy Danila A. ^1,2 , Coffey Aaron M. ^3,4,5,6 , Truong Milton L. ^3,4,5,6 , Salnikov Oleg G. ^1,2 , Khudorozhkov Alexander K. ⁷ , Inozemtseva Elizaveta A. ⁷ , Prosvirin Igor P. ⁷ , Bukhtiyarov Valery I. ⁷ , Waddell Kevin W. ^3,4,5,6 , Chekmenev Eduard Y. ^3,4,5,6 , Koptyug Igor V. ^1,2

Affiliations

1	Laboratory of Magnetic Resonance Microimaging , International Tomography Center, SB RAS, 3A Institutskaya St., Novosibirsk 630090 (Russia)
2	Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090 (Russia)
3	Institute of Imaging Science, Department of Radiology, Nashville, Tennessee, 37232-2310 (USA)
4	Department of Biomedical Engineering, Nashville, Tennessee, 37232-2310 (USA)
5	Department of Physics and Astronomy, Nashville, Tennessee, 37232-2310 (USA)
6	Department of Biochemistry, Nashville, Tennessee, 37232-2310 (USA)
7	Boreskov Institute of Catalysis SB RAS, 5 Acad. Lavrentiev Pr., Novosibirsk 630090 (Russia)

Funding (14)

1	Federal Agency for Scientific Organizations	V.45.3.2.
2	Russian Foundation for Basic Research	12-03-00403
3	Russian Foundation for Basic Research	14-03-00374
4	Russian Foundation for Basic Research	14-03-31239 (01201450183)
5	Siberian Branch of the Russian Academy of Sciences	57
6	Siberian Branch of the Russian Academy of Sciences	60
7	Siberian Branch of the Russian Academy of Sciences	61
8	Siberian Branch of the Russian Academy of Sciences	122
9	Президиум РАН	5.1.1
10	National Institutes of Health	3R00A134749-02S1
11	National Institutes of Health	5P50 CA128323-03
12	National Institutes of Health	R21 GM107947 5R00 CA134749-03
13	Council for Grants of the President of the Russian Federation	МК-4391.2013.3
14	United States Department of Defense	W81XWH-12-1-0159/BC112431

Several supported metal catalysts were synthesized, characterized, and tested in heterogeneous hydrogenation of propene with parahydrogen to maximize nuclear spin hyperpolarization of propane gas using parahydrogen induced polarization (PHIP). The Rh/TiO2 catalyst with a metal particle size of 1.6 nm was found to be the most active and effective in the pairwise hydrogen addition and robust, demonstrating reproducible results with multiple hydrogenation experiments and stability for ≥1.5 years. 3D (1) H magnetic resonance imaging (MRI) of 1 % hyperpolarized flowing gas with microscale spatial resolution (625×625×625 μm(3) ) and large imaging matrix (128×128×32) was demonstrated by using a preclinical 4.7 T scanner and 17.4 s imaging scan time.

Kovtunov K.V. , Barskiy D.A. , Coffey A.M. , Truong M.L. , Salnikov O.G. , Khudorozhkov A.K. , Inozemtseva E.A. , Prosvirin I.P. , Bukhtiyarov V.I. , Waddell K.W. , Chekmenev E.Y. , Koptyug I.V.
High-Resolution 3D Proton MRI of Hyperpolarized Gas Enabled by Parahydrogen and Rh/TiO2 Heterogeneous Catalyst

Chemistry - A European Journal. 2014. V.20. N37. P.11636-11639. DOI: 10.1002/chem.201403604, 10.1002/chem.201404052, 10.1002/chem.201490154 WOS Scopus РИНЦ ANCAN OpenAlex

Full text from publisher

Submitted:	May 20, 2014
Published online:	Jun 24, 2014
Published print:	Sep 8, 2014

Web of science:	WOS:000341630500003
Scopus:	2-s2.0-84906835041
Elibrary:	23986904
Chemical Abstracts:	2014:1025894
Chemical Abstracts (print):	161:591726
OpenAlex:	W2052220397

DB	Citing
Web of science	74
Scopus	75
Elibrary	73
OpenAlex	78