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Glycine: the Gift that Keeps on Giving Review

Journal Israel Journal of Chemistry
ISSN: 0021-2148 , E-ISSN: 1869-5868
Output data Year: 2021, Volume: 61, Number: 11-12, Pages: 828-850 Pages count : 23 DOI: 10.1002/ijch.202100103
Tags Biomedical applications · Crystal growth · High-pressure chemistry · Interfaces · Polymorphism
Authors Boldyreva Elena 1,2
Affiliations
1 Novosibirsk State University, ul. Pirogova, 2, Novosibirsk 630090, Russian Federation
2 Boreskov Institute of Catalysis Siberian Branch of Russian Academy of Sciences, Lavrentieva ave., 5, Novosibirsk 630090, Russian Federation

Funding (1)

1 Ministry of Science and Higher Education of the Russian Federation 0239-2021-0002

Abstract: Glycine is a small molecule. It cannot change its conformation and is achiral. Despite the apparent simplicity, glycine shows endless diversity in its behavior over many phenomena. It was the first amino acid for which polymorphism was reported, first on crystallization and then on hydrostatic compression. The polymorphs differ in their physical properties and their biological activity. Glycine clusters persist in solution, leading to “solution memory”. Phenomena at interfaces are critically important for crystal growth, dissolution, and for physical properties, which can be at times unexpected, like polarity in centrosymmetric α-polymorph. It is a great pleasure to remind of these remarkable phenomena in a special issue honoring professors Meir Lahav and Leslie Leiserowitz, who pioneered the study of the behavior of this unique molecule in many respects, and showed how complex and non-trivial phenomena can be at interfaces: between phases and between research fields.
Cite: Boldyreva E.
Glycine: the Gift that Keeps on Giving
Israel Journal of Chemistry. 2021. V.61. N11-12. P.828-850. DOI: 10.1002/ijch.202100103 WOS Scopus РИНЦ ANCAN OpenAlex
Dates:
Submitted: Sep 14, 2021
Accepted: Oct 18, 2021
Published online: Nov 2, 2021
Published print: Dec 1, 2021
Identifiers:
Web of science: WOS:000713866700001
Scopus: 2-s2.0-85118509664
Elibrary: 47522459
Chemical Abstracts: 2021:2432096
Chemical Abstracts (print): 177:317274
OpenAlex: W3208657946
Citing:
DB Citing
Scopus 18
Web of science 17
Elibrary 13
OpenAlex 21
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