To Touch or not to Touch? Fingerprint-Assisted Grinding of Carbamazepine Form III | Sciact - CRIS-system of Boreskov Institute of Catalysis

To Touch or not to Touch? Fingerprint-Assisted Grinding of Carbamazepine Form III Full article

Journal

CrystEngComm
ISSN: 1466-8033

Output data

Year: 2023, Volume: 25, Number: 34, Pages: 4879-4888 Pages count : 9 DOI: 10.1039/d3ce00544e

Tags

PHASE-TRANSFORMATIONS; SOLID-STATE; PHYSICOCHEMICAL PROPERTIES; CRYSTALLOGRAPHIC BEHAVIOR; CRYSTAL-STRUCTURE; CARBOXYLIC-ACIDS; FATTY-ACIDS; HUMAN SWEAT; POLYMORPH; DIHYDRATE

Authors

Zheltikova Daria ¹ , Losev Evgeniy ^1,2,3 , Boldyreva Elena ^1,2

Affiliations

1	Novosibirsk State University, ul. Pirogova, 2, Novosibirsk, 630090, Russia
2	Boreskov Institute of Catalysis SB RAS, Lavrentieva Ave., 5, 630090, Russia
3	Voevodsky Institute of Chemical Kinetics and Combustion SB RAS, Novosibirsk, 630090 Russia

Funding (2)

1	Russian Foundation for Basic Research	19-29-12026
2	Ministry of Science and Higher Education of the Russian Federation	Приоритет 2030

Mechanically induced polymorphic transformation of polymorph III of carbamazepine into form IV was accelerated and brought to completion by contaminating deliberately a milling jar and ball touching them with fingers. In model experiments with additives of water and fatty acids (important components of the fingerprints), carbamazepine dihydrate and carbamazepine form II, respectively, were obtained, without any evidence of form IV, as a result of mechanical treatment under otherwise the same milling conditions. A possible interpretation was suggested

Zheltikova D. , Losev E. , Boldyreva E.
To Touch or not to Touch? Fingerprint-Assisted Grinding of Carbamazepine Form III
CrystEngComm. 2023. V.25. N34. P.4879-4888. DOI: 10.1039/d3ce00544e WOS Scopus РИНЦ AN OpenAlex

Submitted:	May 30, 2023
Accepted:	Jul 21, 2023
Published online:	Jul 21, 2023
Published print:	Sep 14, 2023

Web of science:	WOS:001044387400001
Scopus:	2-s2.0-85168615968
Elibrary:	54381813
Chemical Abstracts:	2023:1660864
OpenAlex:	W4385154499

DB	Citing
Web of science	5
Scopus	5
Elibrary	5
OpenAlex	3